Nanocomposites with Ca and PO(4) release: Effects of reinforcement, dicalcium phosphate particle size and silanization.

Nanocomposites with Ca and PO(4) release: Effects of reinforcement, dicalcium phosphate particle size and silanization. Research Abstract Details 

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Nanocomposites with Ca and PO(4) release: Effects of reinforcement, dicalcium phosphate particle size and silanization. Abstract Text:

Hockin H K Xu,Michael D Weir,Limin Sun,Hockin H K Xu,Michael D Weir,Limin Sun,

OBJECTIVES: Nanoparticles of dicalcium phosphate anhydrous (DCPA) were synthesized in our laboratory for the first time and incorporated into a dental resin. Our goal was to develop a mechanically strong dental composite that has Ca and PO(4) ion release to combat tooth caries, and to investigate the effects of whisker reinforcement, DCPA particle size and silanization. METHODS: DCPA nanoparticles and two larger DCPA particles were used with nano-silica-fused whiskers as fillers in a resin matrix. Composite mechanical properties were measured via three-point flexure, and the release of Ca and PO(4) ions were measured versus time. RESULTS: Using DCPA nanoparticles with a diameter of 112nm, the composite at a DCPA:whisker mass ratio of 1:1 had a flexural strength (mean+/-S.D.; n=5) of (112+/-17)MPa, not significantly different from (112+/-14)MPa of a commercial non-releasing composite; both were higher than (29+/-7)MPa for the composite at DCPA:whisker of 1:0 (p<0.05). The composite with DCPA particle size of 112nm released Ca to a concentration of 0.85mmol/L and PO(4) of 3.48mmol/L, higher than Ca of 0.67mmol/L and PO(4) of 1.11mmol/L using DCPA with 12mum particle size (p<0.05). Silanization of DCPA increased the composite strength at DCPA:whisker of 1:0 compared to that without silanization, but decreased the Ca and PO(4) release (p<0.05). Increasing the DCPA particle surface area increased the Ca and PO(4) release. SIGNIFICANCE: Decreasing the DCPA particle size increased the Ca and PO(4) release; whisker reinforcement increased the composite strength by two- to three-fold. The nano DCPA-whisker composites, with high strength and Ca and PO(4) release, may provide the needed, unique combination of stress-bearing and caries-inhibiting capabilities.

Nanocomposites with Ca and PO(4) release: Effects of reinforcement, dicalcium phosphate particle size and silanization. Publishing Authors By Initials

HH Xu,MD Weir,L Sun,HH Xu,MD Weir,L Sun,

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Nanocomposites with Ca and PO(4) release: Effects of reinforcement, dicalcium phosphate particle size and silanization. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Dental materials : official publication of the Aca

VOLUME: 23

Page Numbers: 1482-91

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ISSN: 0109-5641

DAY: 6

MONTH: 03

YEAR: 2007

Nanocomposites with Ca and PO(4) release: Effects of reinforcement, dicalcium phosphate particle size and silanization. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Nanocomposites with Ca and PO(4) release: Effects of reinforcement, dicalcium phosphate particle size and silanization.

AFFILIATION: Paffenbarger Research Center, American Dental Association Foundation, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA.

Country: England

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MEDLINETA: Dent Mater

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