Nano-aquarium for dynamic observation of living cells fabricated by femtosecond laser direct writing of photostructurable glass.

Nano-aquarium for dynamic observation of living cells fabricated by femtosecond laser direct writing of photostructurable glass. Research Abstract Details 

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Nano-aquarium for dynamic observation of living cells fabricated by femtosecond laser direct writing of photostructurable glass. Abstract Text:

We demonstrate the fabrication of three-dimensional (3-D) hollow microstructures embedded in photostructurable glass by a nonlinear multiphoton absorption process using a femtosecond (fs) laser. Fs laser direct writing followed by annealing and successive wet etching in dilute hydrofluoric (HF) acid solution resulted in the rapid manufacturing of microchips with 3-D hollow microstructures for the dynamic observation of living microorganisms and cells in fresh water. The embedded microchannel structure enables us to analyze the continuous motion of Euglena gracilis. A microchamber with a movable microneedle demonstrates its ability for the elucidation of the information transmission process in Pleurosira laevis. Such microchips, referred to as nano-aquariums realize the efficient and highly functional observation of microorganisms and cells.

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Nano-aquarium for dynamic observation of living cells fabricated by femtosecond laser direct writing of photostructurable glass. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Biomedical microdevices

VOLUME: 10

Page Numbers: 403-10

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ISSN: 1387-2176

DAY: 14

MONTH: Jun

YEAR: 2008

Nano-aquarium for dynamic observation of living cells fabricated by femtosecond laser direct writing of photostructurable glass. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Nano-aquarium for dynamic observation of living cells fabricated by femtosecond laser direct writing of photostructurable glass.

AFFILIATION: RIKEN-The Institute of Physical and Chemical Research, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan, y-hanada@riken.jp.

Country: United States

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MEDLINETA: Biomed Microdevices

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