N-linked carbohydrates act as lumenal maturation and quality control protein tags.

N-linked carbohydrates act as lumenal maturation and quality control protein tags. Research Abstract Details 

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N-linked carbohydrates act as lumenal maturation and quality control protein tags. Abstract Text:

Robert Daniels,Sherri Svedine,Daniel N Hebert,

Protein modifications such as ubiquitination and phosphorylation commonly serve as sorting tags that control the trafficking and stability of a protein within the cytosol. In recent years, N-linked glycans have emerged as key protein modifications for eukaryotic secretory proteins. These modifications support the recruitment of molecular chaperones and sorting receptors, which recognize specific glycoforms. Therefore, glycanases and carbohydrate transferases work in concert with lectin chaperones and receptors to aid in the maturation and quality control of glycoproteins.

N-linked carbohydrates act as lumenal maturation and quality control protein tags. Publishing Authors By Initials

R Daniels,S Svedine,DN Hebert,

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N-linked carbohydrates act as lumenal maturation and quality control protein tags. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Cell biochemistry and biophysics

VOLUME: 41

Page Numbers: 113-38

Journal Abbreviation: Cell Biochem. Biophys.

ISSN: 1085-9195

DAY: 16

MONTH: 09

YEAR: 2004

N-linked carbohydrates act as lumenal maturation and quality control protein tags. Information

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LANGUAGE: eng

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AFFILIATION: Department of Biochemistry and Molecular Biology, Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, MA.

Country: United States

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MEDLINETA: Cell Biochem Biophys

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