Myositis ossificans progressiva. Clinical features of eight patients and their response to treatment.

Myositis ossificans progressiva. Clinical features of eight patients and their response to treatment. Research Abstract Details 

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Myositis ossificans progressiva. Clinical features of eight patients and their response to treatment. Abstract Text:

R Smith,R G Russell,C G Woods,

The clinical features of eight patients with myositis ossificans progressiva are described and the effects of treatment with the diphosphonate EHDP, together with surgical removal of ectopic bone, are assessed. Early correct diagnosis remains unusual, mainly because the significance of the short great toes is unrecognised, and because myositis may be mistaken for bruising, sarcoma or mumps. The diphosphonate disodium etidronate (EDHP) was given to all patients in an attempt to suppress calcification of new lesions; in five of them ectopic bone was removed during the treatment. EHDP sometimes delayed the mineralisation of newly formed bone matrix after surgical removal but this delay could not be predicted. The variable effect of EHDP may depend particularly on the amount absorbed and on the activity of new bone formation.

Myositis ossificans progressiva. Clinical features of eight patients and their response to treatment. Publishing Authors By Initials

R Smith,RG Russell,CG Woods,

For similar organic chemicals: organophosphorus compounds research abstracts see: organic chemicals: organophosphorus compounds research

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Myositis ossificans progressiva. Clinical features of eight patients and their response to treatment. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The Journal of bone and joint surgery. British vol

VOLUME: 58

Page Numbers: 48-57

Journal Abbreviation:

ISSN: 0301-620X

DAY: 14

MONTH: Feb

YEAR: 1976

Myositis ossificans progressiva. Clinical features of eight patients and their response to treatment. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 375355

Myositis ossificans progressiva. Clinical features of eight patients and their response to treatment. Keywords Mesh Terms:

KEYWORDS: Organophosphorus Compounds

MESH TERMS: therapeutic use

Chemical & Substance for Abstract: Myositis ossificans progressiva. Clinical features of eight patients and their response to treatment. Information

Substance Name: Etidronic Acid

Registry Number: 2809-21-4

Grant and Affiliation Information for Myositis ossificans progressiva. Clinical features of eight patients and their response to treatment.

AFFILIATION:

Country: ENGLAND

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MEDLINETA: J Bone Joint Surg Br

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