Background We investigated the relation between risk factors of coronary artery disease (CAD) and myocardial ischemia detected by (201)Tl SPECT in elderly women. Methods 306 women aged >/=75 yr (79.1 +/- 3.6 yr) who underwent pharmacologic (201)Tl SPECT for suspected CAD based on symptoms or CAD risk factors were included. Coronary risk factors were evaluated by medical records, and included diabetes mellitus (DM), hypertension, hypercholesterolemia, cigarette smoking, greater age (>/=80 yr), and obesity. Summed stress score (SSS), summed rest score (SRS), and summed difference score (SDS) were calculated based on stress and redistribution SPECT images for semiquantification. Results The symptomatic group (n = 110) had a 34.5% perfusion defect rate. The asymptomatic group (n = 196) had a significantly lower perfusion defect rate of 16.8%. However, this significantly increased to 29.4% and 22.0% in the presence of diabetes mellitus (DM) and hypertension, respectively. In addition, the summed stress score of asymptomatic patients (12.4 +/- 6.0) was not lower but comparable to that of symptomatic patients (10.0 +/- 6.0). Conclusions In elderly women suspected of CAD, pharmacologic perfusion imaging can be used to identify myocardial ischemia in patients with angina as well as asymptomatic subjects with concurrent DM or hypertension.
Myocardial perfusion defects and coronary risk factors in symptomatic and asymptomatic elderly women. Publishing Authors By Initials
Myocardial perfusion defects and coronary risk factors in symptomatic and asymptomatic elderly women. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: The international journal of cardiovascular imagin
VOLUME: 24
Page Numbers: 277-81
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ISSN: 1569-5794
DAY: 5
MONTH: 09
YEAR: 2007
Myocardial perfusion defects and coronary risk factors in symptomatic and asymptomatic elderly women. Information
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LANGUAGE: eng
NlmUniqueID: 100969716
Myocardial perfusion defects and coronary risk factors in symptomatic and asymptomatic elderly women. Keywords Mesh Terms:
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Grant and Affiliation Information for Myocardial perfusion defects and coronary risk factors in symptomatic and asymptomatic elderly women.
AFFILIATION: Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwondong, Kangnamgu, Seoul, Korea, suesj@samsung.com.
Country: United States
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MEDLINETA: Int J Cardiovasc Imaging
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