Muscle Spasticity

"A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a ""free interval"") followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al.

Abstracts

- Bilateral spastic cerebral palsy--pathogenetic aspects from MRI. Thirty eight children with bilateral spastic cerebral palsy underwent MRI at the age of 5 years and more. Twenty nine showed correlates of periventricular...

- Botulinum toxin A in the management of spastic gait disorders in children and young adults with cerebral palsy: a randomized, double-blind study of "high-dose" versus "low-dose" treatment. The present study was performed to assess dose-response relationships of local botulinum toxin A (BtxA) treatment in children and teenagers with spastic gait...

- Magnetic resonance imaging in an unusual presentation of herpes encephalitis. We report a patient with herpes simplex virus encephalitis who presented with left hemiparesis and progressed to aphasia and generalized spasticity....

- Paralytic ileus: a complication after intrathecal baclofen therapy. INTRODUCTION: Baclofen is frequently used in the management of spasticity. When the therapeutic benefit of oral baclofen is not satisfactory, intrathecal...

- Pharmacokinetics of baclofen in spastic patients receiving multiple oral doses. The pharmacokinetics of racemic baclofen as determined from plasma and urine data in six spastic patients treated with individualized oral doses, 30-80 mg...

- Spasticity and drug therapy. An overview is presented of pathophysiology, classification and measurement of spasticity and of its treatment, especially with dantrolene and baclofen. In...

- The problems of deformity and disability in cerebral palsy. The relationship of deformity and dysfunction has been studied on 67 children with spastic hemiplegia. The usual treatment of conditions resulting from...

- [Electromyografic analysis of spasticity in cerebral palsied children (author's transl)]

- [Electromyographic findings and therapeutic aspects of spasticity]

- [Indications in surgical treatment of spastic talipes equinus in children]

- [Massage in spastic paralysis]

- [Physical revalidation in spasticity: an electrophysiological evaluation of local cryotherapy]

- [Tetrazepam in the treatment of painful muscle spasms] The aim of the study was to examine myorelaxant and analgetic effects of tetrazepam using double-blind controlled random tests. The study comprised two...

- [The pharmacology of spasticity]

- [Treatment of severe spacticity in multiple sclerosis by continuous intrathecal baclofen] BACKGROUND: Successful treatment of severe spasticity represents an imperative of symptomatic therapy of multiple sclerosis (MS) due to a significant...