Multiscale modeling of biomolecular systems: in serial and in parallel.

Multiscale modeling of biomolecular systems: in serial and in parallel. Research Abstract Details 

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Multiscale modeling of biomolecular systems: in serial and in parallel. Abstract Text:

Gary S Ayton,Will G Noid,Gregory A Voth,

Considerable progress has been recently achieved in the multiscale modeling of complex biological processes. Multiscale models have now investigated the structure and dynamics of lipid membranes, proteins, peptides and DNA over length and time scales ranging from the atomic to the macroscopic. Serial multiscale methods that parameterize low-resolution coarse-grained models with data from high-resolution models have studied long time or length scale phenomena that cannot be investigated with atomically detailed models. Parallel multiscale methods that directly couple high- and low-resolution models have efficiently explored slow structural transitions and the importance of long-wavelength fluctuations for biological molecules. The success of such models relies upon new theories and methods for constructing accurate multiscale bridges that transfer information between models with different resolutions.

Multiscale modeling of biomolecular systems: in serial and in parallel. Publishing Authors By Initials

GS Ayton,WG Noid,GA Voth,

For similar biological sciences: biology: computational biology: systems biology research abstracts see: biological sciences: biology: computational biology: systems biology research

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Multiscale modeling of biomolecular systems: in serial and in parallel. Journal Published:

PUBLICATION TYPE: Review

Journal: Current opinion in structural biology

VOLUME: 17

Page Numbers: 192-8

Journal Abbreviation:

ISSN: 0959-440X

DAY: 23

MONTH: 03

YEAR: 2007

Multiscale modeling of biomolecular systems: in serial and in parallel. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9107784

Multiscale modeling of biomolecular systems: in serial and in parallel. Keywords Mesh Terms:

KEYWORDS: Systems Biology

MESH TERMS: chemistry

Chemical & Substance for Abstract: Multiscale modeling of biomolecular systems: in serial and in parallel. Information

Substance Name: DNA

Registry Number: 9007-49-2

Grant and Affiliation Information for Multiscale modeling of biomolecular systems: in serial and in parallel.

AFFILIATION: Center for Biological Modeling and Simulation, University of Utah, Salt Lake City, UT 84112-0850, USA.

Country: England

AGENCY: United States NIGMS

GRANT: GM063796

ACRONYM: GM

MEDLINETA: Curr Opin Struct Biol

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