Multiecho reconstruction for simultaneous water-fat decomposition and T2* estimation.

Multiecho reconstruction for simultaneous water-fat decomposition and T2* estimation. Research Abstract Details 

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Multiecho reconstruction for simultaneous water-fat decomposition and T2* estimation. Abstract Text:

Huanzhou Yu,Charles A McKenzie,Ann Shimakawa,Anthony T Vu,Anja C S Brau,Philip J Beatty,Angel R Pineda,Jean H Brittain,Scott B Reeder,Huanzhou Yu,Charles A McKenzie,Ann Shimakawa,Anthony T Vu,Anja C S Brau,Philip J Beatty,Angel R Pineda,Jean H Brittain,Scott B Reeder,

PURPOSE: To describe and demonstrate the feasibility of a novel multiecho reconstruction technique that achieves simultaneous water-fat decomposition and T2* estimation. The method removes interference of water-fat separation with iron-induced T2* effects and therefore has potential for the simultaneous characterization of hepatic steatosis (fatty infiltration) and iron overload. MATERIALS AND METHODS: The algorithm called "T2*-IDEAL" is based on the IDEAL water-fat decomposition method. A novel "complex field map" construct is used to estimate both R2* (1/T2*) and local B(0) field inhomogeneities using an iterative least-squares estimation method. Water and fat are then decomposed from source images that are corrected for both T2* and B(0) field inhomogeneity. RESULTS: It was found that a six-echo multiecho acquisition using the shortest possible echo times achieves an excellent balance of short scan and reliable R2* measurement. Phantom experiments demonstrate the feasibility with high accuracy in R2* measurement. Promising preliminary in vivo results are also shown. CONCLUSION: The T2*-IDEAL technique has potential applications in imaging of diffuse liver disease for evaluation of both hepatic steatosis and iron overload in a single breath-hold.

Multiecho reconstruction for simultaneous water-fat decomposition and T2* estimation. Publishing Authors By Initials

H Yu,CA McKenzie,A Shimakawa,AT Vu,AC Brau,PJ Beatty,AR Pineda,JH Brittain,SB Reeder,H Yu,CA McKenzie,A Shimakawa,AT Vu,AC Brau,PJ Beatty,AR Pineda,JH Brittain,SB Reeder,

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Multiecho reconstruction for simultaneous water-fat decomposition and T2* estimation. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of magnetic resonance imaging : JMRI

VOLUME: 26

Page Numbers: 1153-61

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ISSN: 1053-1807

DAY: 1

MONTH: Oct

YEAR: 2007

Multiecho reconstruction for simultaneous water-fat decomposition and T2* estimation. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Multiecho reconstruction for simultaneous water-fat decomposition and T2* estimation.

AFFILIATION: Global Applied Science Lab, GE Healthcare, Menlo Park, California, USA. Huanzhou.Yu@ge.com

Country: United States

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MEDLINETA: J Magn Reson Imaging

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