MUC1 and breast cancer.

MUC1 and breast cancer. Research Abstract Details 

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MUC1 and breast cancer. Abstract Text:

V Apostolopoulos,G A Pietersz,I F McKenzie,

The development of an effective immunotherapeutic approach to cancer is now a major focus of research, and despite impressive progress over the last 10 years there are still many hurdles to overcome to elicit an effective immune response which will totally eradicate the cancer. Mucins (MUC1) have attracted interest as potential targets for immunotherapy of cancers of breast, pancreas, ovary and others, and we have demonstrated that mannan, a polymannose carbohydrate is an effective carrier for MUC1 in eliciting a cellular immune response. Several clinical trials are in progress to evaluate the immunogenicity of MUC1 and its suitability as to use for immunotherapy/vaccine for breast cancer.

MUC1 and breast cancer. Publishing Authors By Initials

V Apostolopoulos,GA Pietersz,IF McKenzie,

For similar cells: blood cells: leukocytes: leukocytes, mononuclear: lymphocytes: t-lymphocytes: cd8-positive t-lymphocytes: t-lymphocytes, cytotoxic research abstracts see: cells: blood cells: leukocytes: leukocytes, mononuclear: lymphocytes: t-lymphocytes: cd8-positive t-lymphocytes: t-lymphocytes, cytotoxic research

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MUC1 and breast cancer. Journal Published:

PUBLICATION TYPE: Review

Journal: Current opinion in molecular therapeutics

VOLUME: 1

Page Numbers: 98-103

Journal Abbreviation: Curr. Opin. Mol. Ther.

ISSN: 1464-8431

DAY: 1

MONTH: Feb

YEAR: 1999

MUC1 and breast cancer. Information

Number of References: 37

LANGUAGE: eng

NlmUniqueID: 100891485

MUC1 and breast cancer. Keywords Mesh Terms:

KEYWORDS: T-Lymphocytes, Cytotoxic

MESH TERMS: immunology

Chemical & Substance for Abstract: MUC1 and breast cancer. Information

Substance Name: mannose receptor

Registry Number: 0

Grant and Affiliation Information for MUC1 and breast cancer.

AFFILIATION: Austin Research Institute, Austin and Repatriation Medical Center, Studley Road, Heidelberg, VIC 3084, Australia. v.apostolopoulos@ari.unimelb.edu.au

Country: England

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MEDLINETA: Curr Opin Mol Ther

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