The authors report the case of a 30-year-old woman who was a long-term intranasal cocaine abuser and who presented with transient ischemic attacks and multiple cerebral infarctions that were associated with moyamoya syndrome. The authors suggest that, because of its sympathomimetic effects, chronic cocaine use may promote intracranial arterial stenosis, distal ischemia, and subsequent formation of moyamoya-like vessels. The patient has remained clinically stable with no new episodes of stroke 6 years after undergoing "pial synangiosis" (modified encephaloduroarteriosynangiosis) to revascularize both hemispheres. Cocaine abuse may lead to moyamoya syndrome and may represent a chronic effect on the cerebral vasculature.
Moyamoya syndrome associated with cocaine abuse. Case report. Publishing Authors By Initials
Moyamoya syndrome associated with cocaine abuse. Case report. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Neurosurgical focus
VOLUME: 5
Page Numbers: e7
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ISSN: 1092-0684
DAY: 15
MONTH: Nov
YEAR: 1998
Moyamoya syndrome associated with cocaine abuse. Case report. Information
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LANGUAGE: eng
NlmUniqueID: 100896471
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Grant and Affiliation Information for Moyamoya syndrome associated with cocaine abuse. Case report.
AFFILIATION: Division of Neurosurgery, Albany Medical College, Albany, New York; and Department of Neurosurgery, The Children's Hospital, Division of Neurosurgery, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts.
Country: United States
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MEDLINETA: Neurosurg Focus
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