Mortality of nitrate fertiliser workers.

Mortality of nitrate fertiliser workers. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Mortality of nitrate fertiliser workers. Abstract Text:

An epidemiological cohort study was conducted to investigate the mortality patterns among a group of workers engaged in the production of nitrate based fertilisers. This study was designed to test the hypothesis that individuals exposed to high concentrations of nitrates might be at increased risk of developing cancers, particularly gastric cancer. A total of 1327 male workers who had been employed in the production of fertilisers between 1946 and 1981 and who had been occupationally exposed to nitrates for at least one year were followed up until 1 March 1981. In total, 304 deaths were observed in this group and these were compared with expected numbers calculated from mortality rates in the northern region of England, where the factory was located. Analysis was also carried out separately for a subgroup of the cohort who had been heavily exposed to nitrates--that is, working in an environment likely to contain more than 10 mg nitrate/m3 for a year or longer. In neither the entire cohort nor the subgroup was any significant excess observed for all causes of mortality or for mortality from any of five broad categories of cause or from four specific types of cancer. A small excess of lung cancer was noted more than 20 years after first exposure in men heavily exposed for more than 10 years. That men were exposed to high concentrations of nitrate was confirmed by comparing concentrations of nitrates in the saliva of a sample of currently employed men with control men, employed at the same factory but not in fertiliser production. The men exposed to nitrate had substantially raised concentrations of nitrate in their saliva compared with both controls within the industry and with men in the general population and resident nearby. The results of this study therefore weight against the idea that exposure to nitrates in the environment leads to the formation in vivo of material amounts of carcinogens.

Mortality of nitrate fertiliser workers. Publishing Authors By Initials

For similar fluids and secretions: bodily secretions: saliva research abstracts see: fluids and secretions: bodily secretions: saliva research

PUBMED ID PMID:

MEDLINE DATE:

Mortality of nitrate fertiliser workers. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: British journal of industrial medicine

VOLUME: 43

Page Numbers: 507-15

Journal Abbreviation: Br J Ind Med

ISSN: 0007-1072

DAY: 28

MONTH: Aug

YEAR: 1986

Mortality of nitrate fertiliser workers. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 370637

Mortality of nitrate fertiliser workers. Keywords Mesh Terms:

KEYWORDS: Saliva

MESH TERMS: mortality

Chemical & Substance for Abstract: Mortality of nitrate fertiliser workers. Information

Substance Name: Nitrites

Registry Number: 0

Grant and Affiliation Information for Mortality of nitrate fertiliser workers.

AFFILIATION:

Country: ENGLAND

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Br J Ind Med

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Mortality of nitrate fertiliser workers Related Publications

• A CROSS-NATIONAL STUDY OF BUENOS AIRES AND CHICAGO ADOLESCENTS.
• A study of the chromosome damage persisting after x-ray therapy for ankylosing spondylitis.
• AGE AT ONSET OF LUNG CANCER: SIGNIFICANCE IN RELATION TO EFFECT OF SMOKING.
• Are we winning the war against cancer? A review in memory of Keith Durrant.
• Ballistic arterial trauma to the lower extremity: recent South African experience.
• Cancer of the lung and nose in nickel workers.
• Cancers of the respiratory tract in mustard gas workers.
• Childhood leukaemia in greater London: a search for evidence of clustering.
• DECOMPRESSION SICKNESS AMONG U.S. NAVY OPERATIONAL DIVERS: AN ESTIMATE OF INCIDENCE USING AIR DECOMPRESSION TABLES. RES REP 4-64.
• Epidemiological evidence of the effects of behaviour and the environment on the risk of human cancer.
• Exposure to vinyl chloride and angiosarcoma of the liver: a report of the register of cases.
• Inhibition of cyclin-dependent kinases - a review of the recent patent literature.
• Interpretation of chromosome counts made on bone-marrow cells.
• Investigation of relation between use of oral contraceptives and thromboembolic disease.
• Major epidemics of the 20th century: from coronary thrombosis to AIDS.
• Mortality from cancer and other causes after radiotherapy for ankylosing spondylitis.
• Mortality from lung cancer in asbestos workers 1955.
• Mortality from lung cancer in asbestos workers.
• Mortality of nitrate fertiliser workers.
• Oral contraceptives and thromboembolic disease.
• Organic impairment simulating mental deficiency.
• PEER RATING VALIDITY AS A FUNCTION OF RATER INTELLIGENCE AND RATING SCORE RECEIVED. PROJ MR005.13-5001, SUBTASK 1, REP 24.
• The smoking-induced epidemic.
• The treatment of septicemia of newborn foals with streptomycin and penicillin.
• Tumours in a tropical country. Foreword.
• Was the study big enough? Two "café" rules (Editorial).
• [Bacteriological investigations on albothyl used in leukorrhea therapy.]
• [Not Available.]
• [Not Available.]
• [Used motor oil poisoning in cattle. Report of a clinical case]