Morphological subtyping of papillary renal cell carcinoma: clinicopathological characteristics and prognosis.

Morphological subtyping of papillary renal cell carcinoma: clinicopathological characteristics and prognosis. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Morphological subtyping of papillary renal cell carcinoma: clinicopathological characteristics and prognosis. Abstract Text:

Shinichi Yamashita,Naomasa Ioritani,Katsuhiko Oikawa,Masataka Aizawa,Mareyuki Endoh,Yoichi Arai,Shinichi Yamashita,Naomasa Ioritani,Katsuhiko Oikawa,Masataka Aizawa,Mareyuki Endoh,Yoichi Arai,

AIM: The aim of the study was to evaluate the clinicopathological and prognostic significance of morphological subtyping of papillary renal cell carcinoma (PRCC). METHODS: The patients treated for renal cell carcinoma in our department from January 1985 to March 2006 were evaluated retrospectively. Thirty-two of the 591 patients (5.4%) were diagnosed with PRCC. To determine the prognostic factors, we re-evaluated the pathological stage according to the 2002 TNM classification of malignant tumors, and the tumor type of renal cell carcinoma according to the 2004 World Health Organization histological classification. Survival was analysed using the Kaplan-Meier method and the log-rank test. RESULTS: The age at diagnosis ranged from 33 to 81 years (median: 63 years old) and the follow-up time after the surgical treatment ranged from 4 to 191 months (median: 54 months). The cancer-specific 5-year survival rate of the 32 PRCC patients was 74%. Pathologically, 17 patients (53%) and 15 patients (47%) were diagnosed with type 1 and type 2 PRCC, respectively. The type 2 PRCC patients had a significantly higher tumor grade (P < 0.001), a more advanced stage (P < 0.001), more frequent vascular invasion (P < 0.001), and a higher sarcomatoid component (P = 0.038) compared to the type 1 PRCC patients. The type 1 patients had a better cancer-specific 5-year survival rate than the type 2 patients (94% vs 50%) (P = 0.008). CONCLUSION: The morphological subtyping of PRCC is significantly associated with clinicopathological features and the prognosis. Our results provide evidence of the clinical utility of dividing PRCC into two subtypes.

Morphological subtyping of papillary renal cell carcinoma: clinicopathological characteristics and prognosis. Publishing Authors By Initials

S Yamashita,N Ioritani,K Oikawa,M Aizawa,M Endoh,Y Arai,S Yamashita,N Ioritani,K Oikawa,M Aizawa,M Endoh,Y Arai,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Morphological subtyping of papillary renal cell carcinoma: clinicopathological characteristics and prognosis. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: International journal of urology : official journa

VOLUME: 14

Page Numbers: 679-83

Journal Abbreviation: Int. J. Urol.

ISSN: 0919-8172

DAY: 7

MONTH: Aug

YEAR: 2007

Morphological subtyping of papillary renal cell carcinoma: clinicopathological characteristics and prognosis. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9440237

Morphological subtyping of papillary renal cell carcinoma: clinicopathological characteristics and prognosis. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Morphological subtyping of papillary renal cell carcinoma: clinicopathological characteristics and prognosis. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Morphological subtyping of papillary renal cell carcinoma: clinicopathological characteristics and prognosis.

AFFILIATION: Department of Urology, Sendai Shakaihoken Hospital, Sendai, Japan. yamashita@uro.med.tohoku.ac.jp

Country: Australia

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Int J Urol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Morphological subtyping of papillary renal cell carcinoma: clinicopathological characteristics and prognosis Related Publications

• A case of two-humped hydrometra with a recurrent uterine cervical cancer.
• A fMRI study of the Cross-Modal Interaction in the Brain with an Adaptable EMG Prosthetic Hand with Biofeedback.
• Absorption Characteristics Evaluation from Pulsed Photo-thermal Radiometry in the Determination of Lung Air-leak Integrity by Vital Staining.
• Accidental carbon monoxide poisoning at home in Japan.
• Age-related vascular stiffness and left ventricular size after myocardial infarction.
• Central nervous system disease complicating Mycoplasma pneumoniae.
• Déjà vu experiences in schizophrenia: relations with psychopathology and antipsychotic medication.
• Evaluation of chewing and swallowing disorders among frail community-dwelling elderly individuals.
• Event-related desynchronization of frontal-midline theta rhythm during preconscious auditory oddball processing.
• Factors affecting guanine nucleotide binding to rat AMPA receptors.
• False positive or true positive troponin in patients presenting with chest pain but 'normal' coronary arteries: lessons from cardiac MRI.
• Genetic analysis of the TrkB gene and schizophrenia in the Japanese population: Juntendo University Schizophrenia Projects (JUSP).
• Hospitalization for medical comorbidities among psychiatric patients in Tokyo.
• Immunohistochemical detection of L-DOPA-derived dopamine within serotonergic fibers in the striatum and the substantia nigra pars reticulata in Parkinsonian model rats.
• Incidental testicular cancers that subsequently developed in oligozoospermic and azoospermic patients: report of three cases.
• Increased plasma glutamate by antipsychotic medication and its relationship to glutaminase 1 and 2 genotypes in schizophrenia -- Juntendo University Schizophrenia Projects (JUSP).
• Intravenous extended liposarcoma arising from renal sinus.
• Long-term survival and risk of second cancers after radiotherapy for cervical cancer.
• Morphological subtyping of papillary renal cell carcinoma: clinicopathological characteristics and prognosis.
• New shape memory alloy actuator: design and application in the prosthetic hand.
• Prolonged and fluctuating giant T-wave inversion after electroconvulsive therapy.
• Protection of cerebellar granule cells by tocopherols and tocotrienols against methylmercury toxicity.
• Psychological distress in Japanese men with localized prostate cancer.
• Reconstruction of a severe maxillofacial deformity after tumorectomy and irradiation using distraction osteogenesis and LeFort I osteotomy before vascularized bone graft.
• Seven cases of late-life depression treated with cilostazol-augmented therapy.
• Structure-activity Relationships of Neoechinulin A Analogues with Cytoprotection against Peroxynitrite-induced PC12 Cell Death.
• Two distinct controls of mitotic cdk1/cyclin B1 activity requisite for cell growth prior to cell division.
• Type I platelet-activating factor acetylhydrolase catalytic subunits over-expression induces pleiomorphic nuclei and centrosome amplification.
• [Experience of complete Carney's triad showing pulmonary hamartoma associated with gastrointestinal stromal tumor and para-arotic paraganglioma]
• [The component of ubiquitin-positive inclusions in ALS]