AIM: To provide the morphological evidence on participating in the adhesive function of human umbilical vein endothelial cells by CD226. METHODS: Human umbilical vein endothelial cells(HUVECs) were cultured and the effect of CD226 on the adhesion between activated HUVEC and activated PBMC were observed by Leica inverted microscope and scanning electron microscope. RESULTS: Fusion protein CD226/Ig could block the adhesion between activated HUVECs and activated PBMC markedly. CONCLUSION: CD226 was a novel inducible adhesion molecule expressed on activated endothelial cells, which may possess important physiological and pathological function.
[Morphological evidence on participating in adhesive function of human umbilical vein endothelial cells by CD226] Publishing Authors By Initials
[Morphological evidence on participating in adhesive function of human umbilical vein endothelial cells by CD226] Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese jour
VOLUME: 19
Page Numbers: 397-9
Journal Abbreviation: Xi Bao Yu Fen Zi Mian Yi Xue Z
ISSN: 1007-8738
DAY: 27
MONTH: Jul
YEAR: 2003
[Morphological evidence on participating in adhesive function of human umbilical vein endothelial cells by CD226] Information
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LANGUAGE: chi
NlmUniqueID: 101139110
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AFFILIATION: Department of Immunology, Fourth Military Medical University, Xi'an 710032, China.
Country: China
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MEDLINETA: Xi Bao Yu Fen Zi Mian Yi Xue Z
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