Morphologic analysis of common atrioventricular valves in patients with right atrial isomerism.

Morphologic analysis of common atrioventricular valves in patients with right atrial isomerism. Research Abstract Details 

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Morphologic analysis of common atrioventricular valves in patients with right atrial isomerism. Abstract Text:

Y Kawahira,H Kishimoto,H Kawata,S Ikawa,H Ueda,T Nakajima,F Kayatani,N Inamura,T Nakada,

The objective of the study was to examine the relation between the morphology of the common atrioventricular valve and regurgitation of the valve in patients with right atrial isomerism. We examined seven consecutive patients with documented right atrial isomerism who subsequently underwent postmortem examination during a 10-year period. The degree of regurgitation and the diameters of the common valve were evaluated via cineangiography, and the site of regurgitation was evaluated by echocardiography. The morphology of the common atrioventricular valve was assessed further at autopsy. Cineangiography revealed valve diameters ranging from 14.8 to 27.8 mm (mean 20.9 mm). Valvar regurgitation was revealed within 2 months of birth in all patients. Regurgitation abruptly worsened in three patients after placement of a Blalock-Taussig shunt or a central shunt and postintubation. Autopsies revealed that the common atrioventricular valve consisted of four leaflets in five patients, and three leaflets in two. The anterior leaflets were large and protruding in all patients, and the lateral leaflets were thickened in six. All patients had a mass consisting of the left lateral leaflets and chordae with direct attachment of the chordae to the ventricular muscle (the right lateral leaflet was attached to the ventricular muscle and immobile in one patient). The lateral leaflets clung to the ventricular wall and exhibited poor movement in six patients. Leaflets with poor mobility corresponded to the regurgitant valvar site as assessed by echocardiography in six patients; and the regurgitation in three patients with acute deterioration occurred at the valvar side with poor mobility. It is concluded that the common atrioventricular valve in patients with right atrial isomerism has morphologic characteristics that may be associated with valvar regurgitation and malignant potential for abrupt deterioration after replacement of systemic-pulmonary shunting.

Morphologic analysis of common atrioventricular valves in patients with right atrial isomerism. Publishing Authors By Initials

Y Kawahira,H Kishimoto,H Kawata,S Ikawa,H Ueda,T Nakajima,F Kayatani,N Inamura,T Nakada,

For similar cardiovascular diseases: heart diseases: heart valve diseases: tricuspid valve insufficiency research abstracts see: cardiovascular diseases: heart diseases: heart valve diseases: tricuspid valve insufficiency research

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MEDLINE DATE: 1997 Mar-Apr

Morphologic analysis of common atrioventricular valves in patients with right atrial isomerism. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Pediatric cardiology

VOLUME: 18

Page Numbers: 107-11

Journal Abbreviation: Pediatr Cardiol

ISSN: 0172-0643

DAY: 20

MONTH: 02

YEAR: 2008

Morphologic analysis of common atrioventricular valves in patients with right atrial isomerism. Information

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LANGUAGE: eng

NlmUniqueID: 8003849

Morphologic analysis of common atrioventricular valves in patients with right atrial isomerism. Keywords Mesh Terms:

KEYWORDS: Tricuspid Valve Insufficiency

MESH TERMS: pathology

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Grant and Affiliation Information for Morphologic analysis of common atrioventricular valves in patients with right atrial isomerism.

AFFILIATION: Department of Cardiovascular Surgery, Osaka Medical Center and Research Institute for Maternal and Child Health, Izumi, Osaka 590-02, Japan.

Country: UNITED STATES

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MEDLINETA: Pediatr Cardiol

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