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Morbidity risk for psychiatric disorders in families of probands with affective disorders divided according to levels of platelet MAO activity.

Morbidity risk for psychiatric disorders in families of probands with affective disorders divided according to levels of platelet MAO activity. Research Abstract Details 

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  • Morbidity risk for psychiatric disorders in families of probands with affective disorders divided according to levels of platelet MAO activity. Abstract Text:

    In a series comprising 166 subjects with affective disorders, the lowest and highest quartiles in the male and female platelet monoamine oxidase (MAO) distribution, respectively, were included. The morbidity risk in the first-degree relatives (parents and siblings) of these low and high platelet MAO subjects was determined. First-degree relatives of low platelet MAO probands were found to have an increased morbidity risk for neurotic-reactive depressions and for alcoholism. The results seem to be in line with the biological high-risk paradigm, indicating that platelet MAO could be a biological marker for increased vulnerability. First-degree relatives of high platelet MAO probands were found to have an increased morbidity risk for bipolar affective disorders.

    Morbidity risk for psychiatric disorders in families of probands with affective disorders divided according to levels of platelet MAO activity. Publishing Authors By Initials

    For similar epidemiologic factors: sex factors research abstracts see: epidemiologic factors: sex factors research

    PUBMED ID PMID:

    MEDLINE DATE:

    Morbidity risk for psychiatric disorders in families of probands with affective disorders divided according to levels of platelet MAO activity. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Psychiatry research

    VOLUME: 15

    Page Numbers: 271-9

    Journal Abbreviation: Psychiatry Res

    ISSN: 0165-1781

    DAY: 17

    MONTH: Aug

    YEAR: 1985

    Morbidity risk for psychiatric disorders in families of probands with affective disorders divided according to levels of platelet MAO activity. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 7911385

    Morbidity risk for psychiatric disorders in families of probands with affective disorders divided according to levels of platelet MAO activity. Keywords Mesh Terms:

    KEYWORDS: Sex Factors

    MESH TERMS: blood

    Chemical & Substance for Abstract: Morbidity risk for psychiatric disorders in families of probands with affective disorders divided according to levels of platelet MAO activity. Information

    Substance Name: Monoamine Oxidase

    Registry Number: EC 1.4.3.4

    Grant and Affiliation Information for Morbidity risk for psychiatric disorders in families of probands with affective disorders divided according to levels of platelet MAO activity.

    AFFILIATION:

    Country: NETHERLANDS

    NETHERLANDS Research PublicationNETHERLANDS Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Psychiatry Res

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

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