Monoclonal antibodies.

Monoclonal antibodies. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Monoclonal antibodies. Abstract Text:

Monoclonal antibodies (mabs) are powerful tools for the quantification, detection, and targeting of specific molecules. Allergen-specific mabs are important for the quantification of major allergens in allergen preparations used for allergen-specific immunotherapy and allergy diagnosis. Indeed, progress in the understanding of the mechanisms of the immunological responses underlying allergic disease would not have been possible without the use of mabs. Quantification assays are also important in the assessment of environmental allergen exposure and monitoring of avoidance procedures.Mabs against human IgE provide the basis for various test systems for the detection of specific and nonspecific IgE. Mabs raised against IgE or defined cytokines or cytokine receptors have potential as neutralizing reagents in vivo for the treatment of allergic diseases.Allergen-specific mabs are also valuable tools for the localization of allergens within their source material and the characterization of allergens derived from natural sources and by recombinant technologies. Furthermore they are often used for the isolation of allergens from complex extracts by affinity chromatography.The procedure described in this chapter has been used successfully to produce mabs against numerous allergens from house dust mites, insect venoms, cat, hens egg white, tree-, grass-, and herb pollens, and fungi, with the ultimate aim of obtaining matched antibody pairs to establish two-site binding assays for the quantification of major allergens. The method has also been used successfully to generate mabs against human IgE.

Monoclonal antibodies. Publishing Authors By Initials

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Monoclonal antibodies. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Methods in molecular medicine

VOLUME: 138

Page Numbers: 183-96

Journal Abbreviation: Methods Mol. Med.

ISSN: 1543-1894

DAY: 9

MONTH: 07

YEAR: 2008

Monoclonal antibodies. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101123138

Monoclonal antibodies. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Monoclonal antibodies. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Monoclonal antibodies.

AFFILIATION: Allergopharma Joachim Ganzer KG, Germany.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Methods Mol Med

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Monoclonal antibodies Related Publications

• Antibacterial action of commercial nitromersol preparations.
• Calibrated leak balloon microcatheter: a device for arterial exploration and occlusive therapy.
• Clinical effects of immunotherapy with genetically modified recombinant birch pollen Bet v 1 derivatives.
• Clinical experience with recombinant pollen allergens.
• Condensation of hydroxy and methoxy N-methylbenzylamines with heterocyclic chlorides.
• Cytology of bronchial secretions; its role in the diagnosis of cancer.
• Development of a homogeneous high-throughput live-cell g-protein-coupled receptor binding assay.
• Diagnosis of cancer of the lung by the cytologic method.
• Effects of estrogen and prostaglandin on progesterone-delayed farrowing.
• Effects of sensorimotor adaptation training on functional mobility in older adults.
• MR imaging of corpus callosotomy.
• Methaqualone--a sedative or mild tranquilizer for geriatric patients.
• Monoclonal antibodies.
• Occupational therapist--observer or evaluator?
• Opening the queen's closet: Henrietta Maria, Elizabeth Cromwell, and the politics of cookery.
• Rathke's cleft cyst as a secondary cause of headache:a case report.
• Remote effects of neuroblastoma.
• The School Nurse as a Health Educator.
• The effect of increasing inertia upon vertical ground reaction forces and temporal kinematics during locomotion.
• The magnetic susceptibility of atomic iodine.
• The micro-estimation and origin of methylamine in Mercurialis perennis L.
• The micro-estimation and origin of trimethylamine in Chenopodium vulvaria L.
• The relations between cognition and the independent living skill of shopping in people with schizophrenia.
• Traumatic pericallosal artery aneurysm.