Molecular signatures define myogenic stem cell populations.

Molecular signatures define myogenic stem cell populations. Research Abstract Details 

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Molecular signatures define myogenic stem cell populations. Abstract Text:

Cindy M Martin,Jamie L Russell,Anwarul Ferdous,Daniel J Garry,

Developmental and regenerative mechanisms are directed by stem cell populations. Skeletal muscle is a dynamic tissue that is capable of adapting to stress and severe injury due to a resident somatic stem cell population. In response to a severe injury that destroys upward of 90% of the tissue, skeletal muscle efficiently and reproducibly regenerates damaged tissue and restores the cellular architecture within a 2-wk period. Recent studies have localized and examined the molecular regulation of skeletal muscle stem cell populations using emerging molecular biological technologies. These studies enhance the understanding of the regulatory mechanisms that direct the somatic stem cell populations and the role they play in development and regeneration. Furthermore, these basic science studies will serve as a platform for future therapies directed toward patients with myopathic diseases.

Molecular signatures define myogenic stem cell populations. Publishing Authors By Initials

CM Martin,JL Russell,A Ferdous,DJ Garry,

For similar cells: stem cells research abstracts see: cells: stem cells research

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Molecular signatures define myogenic stem cell populations. Journal Published:

PUBLICATION TYPE: Review

Journal: Stem cell reviews

VOLUME: 2

Page Numbers: 37-42

Journal Abbreviation:

ISSN: 1550-8943

DAY: 3

MONTH: 12

YEAR: 2006

Molecular signatures define myogenic stem cell populations. Information

Number of References: 38

LANGUAGE: eng

NlmUniqueID: 101255952

Molecular signatures define myogenic stem cell populations. Keywords Mesh Terms:

KEYWORDS: Stem Cells

MESH TERMS: physiology

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Grant and Affiliation Information for Molecular signatures define myogenic stem cell populations.

AFFILIATION: Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX 75390, USA.

Country: United States

AGENCY: United States NIAMS

GRANT: AR47850

ACRONYM: AR

MEDLINETA: Stem Cell Rev

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