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[Molecular mechanisms of double strand break repair in eukaryotes]

[Molecular mechanisms of double strand break repair in eukaryotes] Research Abstract Details 

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  • [Molecular mechanisms of double strand break repair in eukaryotes] Abstract Text:

    v g korolevV G Korolev,

    Genome stability is of primary importance for the survival and for the proper functioning of all organisms. Double strand breaks (DSBs) arise spontaneously during growth, or can be created by external insults. In response to even a single DSB, organisms must trigger series of events to promote repair of the DNA damage in order to survive and restore chromosome integrity. In doing so, cells must regulate a fine balance between potentially competing DSB repair pathways. Much of what we know today on the mechanisms of repair in eukaryotes come from studies carried out in budding yeast. In this review, the main attention is focused on exciting new work eminating from yeast research that provides fresh insights into the DSB repair process.

    [Molecular mechanisms of double strand break repair in eukaryotes] Publishing Authors By Initials

    vg korolevVG Korolev,

    For similar fungi: ascomycota: schizosaccharomyces research abstracts see: fungi: ascomycota: schizosaccharomyces research

    PUBMED ID PMID:

    MEDLINE DATE: 2007 Jul-Aug

    [Molecular mechanisms of double strand break repair in eukaryotes] Journal Published:

    PUBLICATION TYPE: Review

    Journal: Radiatsionnaia biologiia, radioecologiia / Rossiĭ

    VOLUME: 47

    Page Numbers: 389-401

    Journal Abbreviation:

    ISSN: 0869-8031

    DAY: 3

    MONTH: 12

    YEAR: 2007

    [Molecular mechanisms of double strand break repair in eukaryotes] Information

    Number of References: 139

    LANGUAGE: rus

    NlmUniqueID: 9317212

    [Molecular mechanisms of double strand break repair in eukaryotes] Keywords Mesh Terms:

    KEYWORDS: Schizosaccharomyces

    MESH TERMS: metabolism

    Chemical & Substance for Abstract: [Molecular mechanisms of double strand break repair in eukaryotes] Information

    Substance Name: Histones

    Registry Number: 0

    Grant and Affiliation Information for [Molecular mechanisms of double strand break repair in eukaryotes]

    AFFILIATION:

    Country: Russia (Federation)

    Russia (Federation) Research PublicationRussia (Federation) Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Radiats Biol Radioecol

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

    Molecular mechanisms of double strand break repair in eukaryotes Related Publications

     

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