Intraductal papillary-mucinous neoplasms of the pancreas show characteristic clinicopathological and molecular pathobiological features which are distinct from those of conventional ductal adenocarcinomas. Alterations of KRAS, AKT/PKB, CDKN2A, TP53, SMAD4, STK11/LKB1, and DUSP6, and other molecular alterations, including global expression studies as well as their clinical implications, are discussed.
Molecular genetics of intraductal papillary-mucinous neoplasms of the pancreas. Publishing Authors By Initials
Molecular genetics of intraductal papillary-mucinous neoplasms of the pancreas. Journal Published:
PUBLICATION TYPE: Review
Journal: Journal of hepato-biliary-pancreatic surgery
VOLUME: 14
Page Numbers: 233-7
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ISSN: 0944-1166
DAY: 29
MONTH: 05
YEAR: 2007
Molecular genetics of intraductal papillary-mucinous neoplasms of the pancreas. Information
Number of References: 47
LANGUAGE: eng
NlmUniqueID: 9431940
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Grant and Affiliation Information for Molecular genetics of intraductal papillary-mucinous neoplasms of the pancreas.
AFFILIATION: International Research and Educational Institute for Integrated Medical Sciences, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Country: Japan
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MEDLINETA: J Hepatobiliary Pancreat Surg
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