Molecular cloning and sequence analysis of full-length cDNA coding for mouse contrapsin.

Molecular cloning and sequence analysis of full-length cDNA coding for mouse contrapsin. Research Abstract Details 

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Molecular cloning and sequence analysis of full-length cDNA coding for mouse contrapsin. Abstract Text:

Y Suzuki,K Yamamoto,H Sinohara,

Four overlapping cDNA clones encoding contrapsin were isolated from a mouse liver cDNA library constructed in the expression vector, lambda gt11. M13 vector sequence analysis revealed that contrapsin cDNA contained an open reading frame of 1,254 bases encoding 418 amino acids. The N-terminal amino acid sequence of the isolated contrapsin matched residues 30 to 48 of the sequence deduced on nucleotide analysis. One clone, which had the longest 3' untranslated region, contained two sets of tandem polyadenylation signals, AATACA and AATAAA, which were located 497 bases apart, while the remaining three clones terminated at the first signal. The entire reading frame sequence of contrapsin cDNA showed 64% homology with that of human alpha-1-antichymotrypsin.

Molecular cloning and sequence analysis of full-length cDNA coding for mouse contrapsin. Publishing Authors By Initials

Y Suzuki,K Yamamoto,H Sinohara,

For similar chemical actions and uses: pharmacologic actions: molecular mechanisms of pharmacological action: enzyme inhibitors: protease inhibitors: serine proteinase inhibitors: trypsin inhibitors research abstracts see: chemical actions and uses: pharmacologic actions: molecular mechanisms of pharmacological action: enzyme inhibitors: protease inhibitors: serine proteinase inhibitors: trypsin inhibitors research

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Molecular cloning and sequence analysis of full-length cDNA coding for mouse contrapsin. Journal Published:

PUBLICATION TYPE: Review

Journal: Journal of biochemistry

VOLUME: 108

Page Numbers: 344-6

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Sep

YEAR: 1990

Molecular cloning and sequence analysis of full-length cDNA coding for mouse contrapsin. Information

Number of References: 15

LANGUAGE: eng

NlmUniqueID: 376600

Molecular cloning and sequence analysis of full-length cDNA coding for mouse contrapsin. Keywords Mesh Terms:

KEYWORDS: Trypsin Inhibitors

MESH TERMS: genetics

Chemical & Substance for Abstract: Molecular cloning and sequence analysis of full-length cDNA coding for mouse contrapsin. Information

Substance Name: DNA

Registry Number: 9007-49-2

Grant and Affiliation Information for Molecular cloning and sequence analysis of full-length cDNA coding for mouse contrapsin.

AFFILIATION: Department of Biochemistry, Kinki University School of Medicine, Osaka.

Country: JAPAN

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MEDLINETA: J Biochem

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ACCESSION NUMBER: D00725

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