Molecular characterization and comparison of plasmid content in seven different strains of Neisseria gonorrhoeae.

Molecular characterization and comparison of plasmid content in seven different strains of Neisseria gonorrhoeae. Research Abstract Details 

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Molecular characterization and comparison of plasmid content in seven different strains of Neisseria gonorrhoeae. Abstract Text:

R B Aalen,W B Gundersen,

The plasmid content of one penicillin sensitive and six penicillin resistant strains of Neisseria gonorrhoeae has been examined. All strains harbour a small, phenotypically cryptic plasmid of 4.1 kilo base pairs (kb). Four of the penicillin resistant strains carry a beta-lactamase-producing plasmid of 7.3 kb. One of these also carries a large plasmid of about 40 kb. The two remaining penicillin resistant strains harbour a smaller beta-lactamase-producing plasmid of 5.5 kb. The plasmids have been subjected to digestion with a number of restriction endonucleases, and their restriction maps have been compared. Judging by the maps, the cryptic (C-) plasmids show great similarities. Except that two of them have 54 additional base-pairs (bp), and two have a HpaII site instead of a DdeI site, no differences were found. The larger beta-lactamase-producing (B-) plasmids have identical maps. The smaller seem to be homologous with the larger, except for a deletion of 1.8 kb. There is no correlation between the variant of C-plasmid and type of B-plasmid harboured in the penicillin resistant strains. The evolutionary implications suggested by this finding are discussed.

Molecular characterization and comparison of plasmid content in seven different strains of Neisseria gonorrhoeae. Publishing Authors By Initials

RB Aalen,WB Gundersen,

For similar genetic structures: plasmids research abstracts see: genetic structures: plasmids research

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Molecular characterization and comparison of plasmid content in seven different strains of Neisseria gonorrhoeae. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Acta pathologica, microbiologica, et immunologica

VOLUME: 95

Page Numbers: 13-21

Journal Abbreviation:

ISSN: 0108-0180

DAY: 12

MONTH: Feb

YEAR: 1987

Molecular characterization and comparison of plasmid content in seven different strains of Neisseria gonorrhoeae. Information

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LANGUAGE: eng

NlmUniqueID: 8206623

Molecular characterization and comparison of plasmid content in seven different strains of Neisseria gonorrhoeae. Keywords Mesh Terms:

KEYWORDS: Plasmids

MESH TERMS: genetics

Chemical & Substance for Abstract: Molecular characterization and comparison of plasmid content in seven different strains of Neisseria gonorrhoeae. Information

Substance Name: DNA Restriction Enzymes

Registry Number: EC 3.1.21.-

Grant and Affiliation Information for Molecular characterization and comparison of plasmid content in seven different strains of Neisseria gonorrhoeae.

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Country: DENMARK

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MEDLINETA: Acta Pathol Microbiol Immunol

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