Minimized platelet interaction with poly(2-hydroxyethyl methacrylate-block-4-bis(trimethylsilyl)methylstyrene) hydrogel showing anomalously high free water content.

Minimized platelet interaction with poly(2-hydroxyethyl methacrylate-block-4-bis(trimethylsilyl)methylstyrene) hydrogel showing anomalously high free water content. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Minimized platelet interaction with poly(2-hydroxyethyl methacrylate-block-4-bis(trimethylsilyl)methylstyrene) hydrogel showing anomalously high free water content. Abstract Text:

K Kataoka,H Ito,H Amano,Y Nagasaki,M Kato,T Tsuruta,K Suzuki,T Okano,Y Sakurai,

Novel hydrophilic-hydrophobic block copolymers - poly(2-hydroxyethyl methacrylate-block-4-bis(trimethylsilyl)methylstyrene) (poly(HEMA-block-BSMS) or BH polymer) - were prepared as materials potentially useful for blood-contacting devices. Among the BH(X) series including poly(HEMA) itself, platelet adhesion and activation are minimum on the surface of BH(10), the block copolymer composed of 10 mol% of the hydrophobic segment. The unique physicochemical characteristics of BH(10) such as the high free water content and the increased mobility of PHEMA segments seem to play an important role in the prevention of platelet adhesion and activation. The water content of BH(10) was twice that of poly(HEMA) itself, even in the presence of 10 mol% of the hydrophobic moiety [poly(BSMS)]. Further, an anomalous increase in free water content was observed for the BH(10) sample measured by DSC. The glass transition temperature of BH(10) in the dry state was determined to be c. 10 degrees C, which was much lower than that observed for each of the homopolymers (c.f.: Tg [poly(HEMA)] = 70 degrees C; Tg [poly(BSMS)] = 160 degrees C), suggesting an increased mobility of tethered PHEMA segments in the BH(10) film.

Minimized platelet interaction with poly(2-hydroxyethyl methacrylate-block-4-bis(trimethylsilyl)methylstyrene) hydrogel showing anomalously high free water content. Publishing Authors By Initials

K Kataoka,H Ito,H Amano,Y Nagasaki,M Kato,T Tsuruta,K Suzuki,T Okano,Y Sakurai,

For similar natural sciences: chemistry: chemistry, physical: surface properties: wettability research abstracts see: natural sciences: chemistry: chemistry, physical: surface properties: wettability research

PUBMED ID PMID:

MEDLINE DATE:

Minimized platelet interaction with poly(2-hydroxyethyl methacrylate-block-4-bis(trimethylsilyl)methylstyrene) hydrogel showing anomalously high free water content. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biomaterials science. Polymer edition

VOLUME: 9

Page Numbers: 111-29

Journal Abbreviation:

ISSN: 0920-5063

DAY: 20

MONTH: 02

YEAR: 1998

Minimized platelet interaction with poly(2-hydroxyethyl methacrylate-block-4-bis(trimethylsilyl)methylstyrene) hydrogel showing anomalously high free water content. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9007393

Minimized platelet interaction with poly(2-hydroxyethyl methacrylate-block-4-bis(trimethylsilyl)methylstyrene) hydrogel showing anomalously high free water content. Keywords Mesh Terms:

KEYWORDS: Wettability

MESH TERMS: physiology

Chemical & Substance for Abstract: Minimized platelet interaction with poly(2-hydroxyethyl methacrylate-block-4-bis(trimethylsilyl)methylstyrene) hydrogel showing anomalously high free water content. Information

Substance Name: Water

Registry Number: 7732-18-5

Grant and Affiliation Information for Minimized platelet interaction with poly(2-hydroxyethyl methacrylate-block-4-bis(trimethylsilyl)methylstyrene) hydrogel showing anomalously high free water content.

AFFILIATION: Department of Materials Science and Technology, Science University of Tokyo, Noda, Japan.

Country: NETHERLANDS

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Biomater Sci Polym Ed

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Minimized platelet interaction with poly2-hydroxyethyl methacrylate-block-4-bistrimethylsilylmethylstyrene hydrogel showing anomalously high free water content Related Publications

• 20-Hydroxyecdysone regulation of two isoforms of the Ets transcription factor E74 gene in programmed cell death in the silkworm anterior silk gland.
• A low potential iron-sulfur cluster bound to membranes in blue-green algae.
• A new EPR signal associated with photosystem 1 of algal and plant photosynthesis.
• ADP binding to TF1 and its subunits induces ultraviolet spectral changes.
• Action mechanism of bis(allixinato)oxovanadium(IV) as a novel potent insulin-mimetic complex: regulation of GLUT4 translocation and FoxO1 transcription factor.
• Amelioration of Hyperglycemia and Metabolic Syndromes in Type 2 Diabetic KKA(y) Mice by Poly(gamma-glutamic acid)oxovanadium(IV) Complex.
• Coding of spatial information by soma and dendrite of pyramidal cells in the hippocampal CA1 of behaving rats.
• Compliance with inhaled corticosteroid treatment: rates reported by guardians and measured by the pharmacy.
• Derivation of leukemic plasmacytoid dendritic cells coexpressing a progenitor cell surface antigen, CD117, without interferon-alpha production.
• Effect of unsaturated bonds in the sn-2 acyl chain of phosphatidylcholine on the membrane-damaging action of Clostridium perfringens alpha-toxin toward liposomes.
• Effects of Disruption of Homocitrate Synthase Genes on Nostoc sp. Strain PCC 7120 Photobiological Hydrogen Production and Nitrogenase.
• Effects of the amino-carbonyl reaction of ribose and glycine on the formation of the 2(or 5)-ethyl-5(or 2)-methyl-4-hydroxy-3(2H)-furanone aroma component specific to miso by halo-tolerant yeast.
• High-energy inelastic-scattering beamline for electron momentum density study.
• Influence of tongue pressure and width on tongue indentation formation.
• Magnetic fields generated by an induction heating (IH) cook top do not cause genotoxicity in vitro.
• New method for evaluation of tongue-coating status.
• Novel sensing system for glucose based on the complex formation between phenylborate and fluorescent diol compounds.
• Optical and electrophysiological recordings of corticospinal synaptic activity and its developmental change in in vitro rat slice co-cultures.
• Patch-and-glue repair in combination with or without direct suture for cardiac rupture after myocardial infarction.
• Role of heat shock transcription factor in Saccharomyces cerevisiae oxidative stress response.
• Solubilization of the Ecdysone Binding Protein from Anterior Silk Gland Cell Membranes of the Silkworm, Bombyx mori.
• Structure and function of the engineered multicopper oxidase CueO from Escherichia coli--deletion of the methionine-rich helical region covering the substrate-binding site.
• Thermosensitive gold nanoclusters stabilized by well-defined vinyl ether star polymers: reusable and durable catalysts for aerobic alcohol oxidation.
• Two Phenol Compounds from Berchemia racemosa.
• Type III Cu mutants of Myrothecium verrucaria bilirubin oxidase.
• [Esophagitis, esophageal ulcer, gastro-duodenal ulcer, small intestinal ulcer]
• [Faculty development on prosthodontic education--on the basis of the first international clinical prosthodontics educators workshop]
• [New insights into physiological functions of the kinase TAK1]
• [Osseointegrated implant treatment to the region of tumor extirpation in a patient with ameloblastoma]
• [Regulatory mechanism of sleep/wakefulness states by orexin]