Milk fat globule membrane components--a proteomic approach.

Milk fat globule membrane components--a proteomic approach. Research Abstract Details 

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Milk fat globule membrane components--a proteomic approach. Abstract Text:

Maria Cavaletto,Maria Gabriella Giuffrida,Amedeo Conti,Maria Cavaletto,Maria Gabriella Giuffrida,Amedeo Conti,

The milk fat globule membrane (MFGM) is the membrane surrounding lipid droplets during their secretion in the alveolar lumen of the lactating mammary gland. MFGM proteins represent only 1-4% of total milk protein content; nevertheless, the MFGM consists of a complex system of integral and peripheral proteins, enzymes, and lipids. Despite their low classical nutritional value, MFGM proteins have been reported to play an important role in various cellular processes and defense mechanisms in the newborn. Using a proteomic approach, such as high-resolution, two-dimensional electrophoresis followed by direct protein identification by mass spectrometry, it has been possible to comprehensively characterize the subcellular organization of MFGM. This chapter covers the description of MFGM proteomics from the first studies about 10 years ago through the most recent papers. Most of the investigations deal with MFGMs from human and cow milk.

Milk fat globule membrane components--a proteomic approach. Publishing Authors By Initials

M Cavaletto,MG Giuffrida,A Conti,M Cavaletto,MG Giuffrida,A Conti,

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Milk fat globule membrane components--a proteomic approach. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Advances in experimental medicine and biology

VOLUME: 606

Page Numbers: 129-41

Journal Abbreviation: Adv. Exp. Med. Biol.

ISSN: 0065-2598

DAY: 10

MONTH: 01

YEAR: 2008

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LANGUAGE: eng

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AFFILIATION: Biochemistry and Proteomics Section, DISAV Dipartimento Scienze dell' Ambiente e della Vita, Università del Piemonte Orientale, Alessandria, Italy. maria.cavaletto@unipmn.it

Country: United States

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MEDLINETA: Adv Exp Med Biol

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