Microstructural maturation of the human brain from childhood to adulthood.

Microstructural maturation of the human brain from childhood to adulthood. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Microstructural maturation of the human brain from childhood to adulthood. Abstract Text:

C Lebel,L Walker,A Leemans,L Phillips,C Beaulieu,

Brain maturation is a complex process that continues well beyond infancy, and adolescence is thought to be a key period of brain rewiring. To assess structural brain maturation from childhood to adulthood, we charted brain development in subjects aged 5 to 30 years using diffusion tensor magnetic resonance imaging, a novel brain imaging technique that is sensitive to axonal packing and myelination and is particularly adept at virtually extracting white matter connections. Age-related changes were seen in major white matter tracts, deep gray matter, and subcortical white matter, in our large (n=202), age-distributed sample. These diffusion changes followed an exponential pattern of maturation with considerable regional variation. Differences observed in developmental timing suggest a pattern of maturation in which areas with fronto-temporal connections develop more slowly than other regions. These in vivo results expand upon previous postmortem and imaging studies and provide quantitative measures indicative of the progression and magnitude of regional human brain maturation.

Microstructural maturation of the human brain from childhood to adulthood. Publishing Authors By Initials

C Lebel,L Walker,A Leemans,L Phillips,C Beaulieu,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Microstructural maturation of the human brain from childhood to adulthood. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: NeuroImage

VOLUME: 40

Page Numbers: 1044-55

Journal Abbreviation: Neuroimage

ISSN: 1053-8119

DAY: 11

MONTH: 01

YEAR: 2008

Microstructural maturation of the human brain from childhood to adulthood. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9215515

Microstructural maturation of the human brain from childhood to adulthood. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Microstructural maturation of the human brain from childhood to adulthood. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Microstructural maturation of the human brain from childhood to adulthood.

AFFILIATION: Department of Biomedical Engineering, Faculty of Medicine and Dentistry, Room 1098 Research Transition Facility, University of Alberta, Edmonton, Alberta, Canada T6G 2V2.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Neuroimage

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Microstructural maturation of the human brain from childhood to adulthood Related Publications

• Abduction and external rotation in shoulder impingement: an open MR study on healthy volunteers initial experience.
• Asymmetric closure of ischiopubic synchondrosis in pediatric patients: correlation with foot dominance.
• Balanced SSFP imaging of the musculoskeletal system.
• Correction of megavoltage cone-beam CT images for dose calculation in the head and neck region.
• Depth-resolved chromophore analysis of bovine retina and pigment epithelium by photoacoustic spectroscopy.
• Differential expression of claudin-2 along the human intestine: Implication of GATA-4 in the maintenance of claudin-2 in differentiating cells.
• Diffusion tensor tractography of the limbic system.
• Effect of UV irradiation on cut cantaloupe: terpenoids and esters.
• Evolution theory: an overview of its applications in psychiatry.
• Genome size scaling through phenotype space.
• Light exposure in the natural environment: relevance to mood and sleep disorders.
• Messing up with traffic: different effects of antipsychotic agents on glutamate receptor complexes in vivo.
• Microstructural maturation of the human brain from childhood to adulthood.
• Musculoskeletal MRI at 3.0 T: initial clinical experience.
• Musculoskeletal MRI at 3.0 T: relaxation times and image contrast.
• Non-nucleoside inhibitors of the HCV NS5B polymerase: progress in the discovery and development of novel agents for the treatment of HCV infections.
• Pharmacological management of atypical antipsychotic-induced weight gain.
• Recent advances in the pharmacological management of pain.
• Sodium imaging optimization under specific absorption rate constraint.
• Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: a role for endogenous fatty-acid ethanolamides?
• Tako-tsubo cardiomyopathy.
• The local antinociceptive effects of paracetamol in neuropathic pain are mediated by cannabinoid receptors.
• The neurobiology of treatment response to antidepressants and mood stabilizing medications.
• Transparent rendering of intraluminal contrast for 3D polyp visualization at CT colonography.
• Using biphasic CT to reveal gastrointestinal arteriovenous malformations.
• Volume rendering of CT data: applications to the genitourinary tract.
• Volume rendering of tendon-bone relationships using unenhanced CT.
• [Influence of cortisone on the different urinary steroids of patients with congenital hyperplasia of the adrenal cortex.]
• [New light on chronic hypokalemia with urinary corticoid excess; proof of hyperaldosteronuria.]
• [To change death one would have to change life.]