MicroRNAs in malignant progression.

MicroRNAs in malignant progression. Research Abstract Details 

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MicroRNAs in malignant progression. Abstract Text:

Li Ma,Robert A Weinberg,

A growing body of evidence suggests that certain microRNAs (miRNAs) play causal roles in tumorigenesis by regulating genes that control cellular processes such as cell cycle, apoptosis, and differentiation. Lately, work in our laboratory has revealed that a specific miRNA can cause cancer cells to invade and metastasize. Here we review recent progress made in several laboratories concerning the roles played by miRNAs in cancer pathogenesis and metastatic spread, with the focus on the pro-metastatic microRNA, miR-10b, and discuss the future directions and possibilities for clinical applications.

MicroRNAs in malignant progression. Publishing Authors By Initials

L Ma,RA Weinberg,

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MicroRNAs in malignant progression. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Cell cycle (Georgetown, Tex.)

VOLUME: 7

Page Numbers: 570-2

Journal Abbreviation: Cell Cycle

ISSN: 1551-4005

DAY: 31

MONTH: 12

YEAR: 2007

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LANGUAGE: eng

NlmUniqueID: 101137841

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Grant and Affiliation Information for MicroRNAs in malignant progression.

AFFILIATION: Whitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.

Country: United States

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MEDLINETA: Cell Cycle

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