Microcalorimetric and chromatographic investigations of the binding of some pyridine derivatives to cyclodextrins.

Microcalorimetric and chromatographic investigations of the binding of some pyridine derivatives to cyclodextrins. Research Abstract Details 

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Microcalorimetric and chromatographic investigations of the binding of some pyridine derivatives to cyclodextrins. Abstract Text:

S El Gezawi,N Omar,N El Rabbat,H Ueda,J H Perrin,

The binding of some pyridine derivatives to alpha-, beta- and gamma-cyclodextrins has been investigated by microcalorimetry. The strongest binding is to beta-cyclodextrin, but the binding constants are of the order 10(2) M(-1). The binding to beta-cyclodextrin was also investigated by high performance liquid chromatography. The addition of beta-cyclodextrin to the mobile phase allowed separation of molecules with similar binding constants and of racemates in the case of tropicamide.

Microcalorimetric and chromatographic investigations of the binding of some pyridine derivatives to cyclodextrins. Publishing Authors By Initials

S El Gezawi,N Omar,N El Rabbat,H Ueda,JH Perrin,

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Microcalorimetric and chromatographic investigations of the binding of some pyridine derivatives to cyclodextrins. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of pharmaceutical and biomedical analysis

VOLUME: 6

Page Numbers: 399-406

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ISSN: 0731-7085

DAY: 26

MONTH: 07

YEAR: 1988

Microcalorimetric and chromatographic investigations of the binding of some pyridine derivatives to cyclodextrins. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Microcalorimetric and chromatographic investigations of the binding of some pyridine derivatives to cyclodextrins.

AFFILIATION: Department of Pharmacy University of Assiut, Assiut, Egypt.

Country: England

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MEDLINETA: J Pharm Biomed Anal

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