Microarray-based approach for genome-wide survey of nucleotide polymorphisms.

Microarray-based approach for genome-wide survey of nucleotide polymorphisms. Research Abstract Details 

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Microarray-based approach for genome-wide survey of nucleotide polymorphisms. Abstract Text:

Brian W Brunelle,Tracy L Nicholson,Brian W Brunelle,Tracy L Nicholson,Brian W Brunelle,Tracy L Nicholson,

DNA microarrays can be used to detect polymorphic loci in addition to identifying genes or regions that are absent within a genome. A survey such as this offers greater insight into the level of diversification within a species or population, which is useful in organisms that have near-identical genomic content but differ in phenotype. The identification of such variable loci can then lead to the characterization of genes linked to unique biological attributes. Here, we describe a competitive hybridization assay using DNA microarrays as a comparative genomics tool to identify nucleotide polymorphisms among closely related strains of Chlamydia trachomatis.

Microarray-based approach for genome-wide survey of nucleotide polymorphisms. Publishing Authors By Initials

BW Brunelle,TL Nicholson,BW Brunelle,TL Nicholson,BW Brunelle,TL Nicholson,

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Microarray-based approach for genome-wide survey of nucleotide polymorphisms. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Methods in molecular biology (Clifton, N.J.)

VOLUME: 396

Page Numbers: 267-80

Journal Abbreviation: Methods Mol. Biol.

ISSN: 1064-3745

DAY: 20

MONTH: 11

YEAR: 2007

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LANGUAGE: eng

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