Micro-flow injection analysis system: on-chip sample preconcentration, injection and delivery using coupled monolithic electroosmotic pumps.

Micro-flow injection analysis system: on-chip sample preconcentration, injection and delivery using coupled monolithic electroosmotic pumps. Research Abstract Details 

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Micro-flow injection analysis system: on-chip sample preconcentration, injection and delivery using coupled monolithic electroosmotic pumps. Abstract Text:

Fu-Qiang Nie,Mirek Macka,Brett Paull,Fu-Qiang Nie,Mirek Macka,Brett Paull,

A micro-fluidic chip, within which two monolithic electroosmotic pumps are utilised for sample preconcentration, injection and delivery is presented. The monolithic pumps were capable of producing stable and bubble free flow rates at applied voltages below 2 kV, with a current <10 microA. Electrokinetic (EK) sample injection, down to low nano-litre volumes, was quantitatively controlled through applied voltage and injection times, whilst the sample pump delivered a carrier solution to indirectly dispense the sample. A nano-flow sensor (NFS) was used to continuously monitor the flow rate stability of each pump, showing response times of <5-10 s for changes in applied voltage. A capacitively coupled contactless conductivity detector (C(4)D), as an off-chip on-capillary detector, was used to complete the micro-flow injection analysis (FIA) system. A monolithic electroosmotic pump (EOP), modified with an anionic surfactant, was used to demonstrate a novel approach to on-chip cation preconcentration and elution.

Micro-flow injection analysis system: on-chip sample preconcentration, injection and delivery using coupled monolithic electroosmotic pumps. Publishing Authors By Initials

FQ Nie,M Macka,B Paull,FQ Nie,M Macka,B Paull,

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Micro-flow injection analysis system: on-chip sample preconcentration, injection and delivery using coupled monolithic electroosmotic pumps. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Lab on a chip

VOLUME: 7

Page Numbers: 1597-9

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ISSN: 1473-0197

DAY: 2

MONTH: 08

YEAR: 2007

Micro-flow injection analysis system: on-chip sample preconcentration, injection and delivery using coupled monolithic electroosmotic pumps. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Micro-flow injection analysis system: on-chip sample preconcentration, injection and delivery using coupled monolithic electroosmotic pumps.

AFFILIATION: National Centre for Sensor Research, School of Chemical Sciences, Dublin City University, Glasnevin, Dublin 9, Ireland.

Country: England

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MEDLINETA: Lab Chip

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