MF59-adjuvanted subunit influenza vaccine: an improved interpandemic influenza vaccine for vulnerable populations.

MF59-adjuvanted subunit influenza vaccine: an improved interpandemic influenza vaccine for vulnerable populations. Research Abstract Details 

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MF59-adjuvanted subunit influenza vaccine: an improved interpandemic influenza vaccine for vulnerable populations. Abstract Text:

Joan ,David ,Joan ,David ,

Influenza is a highly contagious respiratory disease associated with substantial morbidity and mortality in vulnerable populations, especially the elderly. Influenza viruses are unique in that they undergo small mutations and antigenic variation in their hemagglutinin and neuraminidase genes. Owing to the senescence of the immune system, the ability to mount novel immune responses may be particularly compromised in older people. Fluad (Novartis Vaccines), an MF59-adjuvanted subunit influenza vaccine, was formulated in order to achieve greater immunogenicity in those groups who need a higher protection than that brought about by conventional vaccines. This article summarizes the main characteristics of MF59-adjuvanted subunit influenza vaccine, the clinical effectiveness data that have been generated in recent years and future developments.

MF59-adjuvanted subunit influenza vaccine: an improved interpandemic influenza vaccine for vulnerable populations. Publishing Authors By Initials

J ,D ,J ,D ,

For similar persons: vulnerable populations research abstracts see: persons: vulnerable populations research

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MF59-adjuvanted subunit influenza vaccine: an improved interpandemic influenza vaccine for vulnerable populations. Journal Published:

PUBLICATION TYPE: Review

Journal: Expert review of vaccines

VOLUME: 6

Page Numbers: 659-65

Journal Abbreviation:

ISSN: 1744-8395

DAY: 28

MONTH: Oct

YEAR: 2007

MF59-adjuvanted subunit influenza vaccine: an improved interpandemic influenza vaccine for vulnerable populations. Information

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LANGUAGE: eng

NlmUniqueID: 101155475

MF59-adjuvanted subunit influenza vaccine: an improved interpandemic influenza vaccine for vulnerable populations. Keywords Mesh Terms:

KEYWORDS: Vulnerable Populations

MESH TERMS: immunology

Chemical & Substance for Abstract: MF59-adjuvanted subunit influenza vaccine: an improved interpandemic influenza vaccine for vulnerable populations. Information

Substance Name: Squalene

Registry Number: 111-02-4

Grant and Affiliation Information for MF59-adjuvanted subunit influenza vaccine: an improved interpandemic influenza vaccine for vulnerable populations.

AFFILIATION: Centre de Salut Pública de Castelló, Avda del Mar, 12, E 12100, Castelló, Spain. jpuigb@terra.es

Country: England

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MEDLINETA: Expert Rev Vaccines

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