Methodology of an ongoing, randomized controlled trial to prevent falls through enhanced pharmaceutical care.

Methodology of an ongoing, randomized controlled trial to prevent falls through enhanced pharmaceutical care. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Methodology of an ongoing, randomized controlled trial to prevent falls through enhanced pharmaceutical care. Abstract Text:

Background: Falls are the leading cause of both fatal and nonfatal injuries among adults aged >/=65 years in the United States. Past research suggests that individuals taking multiple medications are at increased risk of falls. Central nervous system-active drugs in particular have been associated with increased risk. Objective: The goal of this research was to describe the design of a study evaluating the effectiveness of a community pharmacy-based falls prevention program. Also presented are the algorithms used to identify high-risk patients based on their prescription profile records and to deliver the experimental intervention. Methods: The study is a randomized controlled trial. The target population was community-dwelling older adults (aged >/=65 years) at high risk for future falls because: (1) they had experienced >/=1 fall within the 12-month period preceding study enrollment; (2) they were currently using >/=4 chronic prescription medications; and (3) they were taking >/=1 of the high-risk medications targeted by the intervention. Participants were recruited using pharmacy prescription profile records. Individuals in the intervention group received a face-to-face medication consultation provided by a community pharmacy resident. Identification of drug therapy problems and therapeutic recommendations was guided by a series of algorithms developed for this study. All participants were followed up for 24 months. The primary study end points were: (1) time to first fall; and (2) proportion of participants who experienced >/=1 fall during the first year of follow-up. Results: Participant enrollment began in September 2005 and was completed in August 2007. A total of 186 individuals were enrolled in the study (mean [SD] age, 74.8 [6.9] years; 132 women, 54 men), and 67 have completed the first year of follow-up. Conclusions: The study is using a rigorous randomized controlled research design, which will enhance the internal validity of its findings. Results of the study, which will be reported after the completion of follow-up data collection activities, will enable us to assess the effects of the intervention on both medication use and the incidence of falls. If the intervention is found to be effective, it will provide a resource for community pharmacists working with older adults at high risk of medication-related falls.

Methodology of an ongoing, randomized controlled trial to prevent falls through enhanced pharmaceutical care. Publishing Authors By Initials

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Methodology of an ongoing, randomized controlled trial to prevent falls through enhanced pharmaceutical care. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The American journal of geriatric pharmacotherapy

VOLUME: 6

Page Numbers: 61-81

Journal Abbreviation:

ISSN: 1543-5946

DAY: 4

MONTH: Jun

YEAR: 2008

Methodology of an ongoing, randomized controlled trial to prevent falls through enhanced pharmaceutical care. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101190325

Methodology of an ongoing, randomized controlled trial to prevent falls through enhanced pharmaceutical care. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Methodology of an ongoing, randomized controlled trial to prevent falls through enhanced pharmaceutical care. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Methodology of an ongoing, randomized controlled trial to prevent falls through enhanced pharmaceutical care.

AFFILIATION: Division of Pharmacy Practice and Experiential Education, School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Am J Geriatr Pharmacother

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Methodology of an ongoing, randomized controlled trial to prevent falls through enhanced pharmaceutical care Related Publications

• A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation.
• Adenocarcinoma of the middle third of the esophagus arising from ectopic gastric mucosa.
• Aspiration of blood from pericardium in treatment of acute cardiac tamponade after injury; further experience, with report of cases.
• Cancer of the stomach.
• Complete transposition of the aorta and the pulmonary artery; experimental observations on venous shunts as corrective procedures.
• Hematology as an aid in the diagnosis of poultry diseases.
• Interfering with extracellular matrix degradation to blunt inflammation.
• Methodology of an ongoing, randomized controlled trial to prevent falls through enhanced pharmaceutical care.
• Neuhauser Lecture: Tetralogy of Fallot: early history and late results.
• Possible therapeutic vaccines for canine myasthenia gravis: implications for the human disease and associated fatigue.
• Post hoc pattern matching: assigning significance to statistically defined expression patterns in single channel microarray data.
• Potential role of high-mobility group box 1 in cystic fibrosis airway disease.
• Predictors of calcium intake patterns: a longitudinal analysis.
• Risky eating behaviors of young adults-implications for food safety education.
• Surgical procedures employed and anatomical variations encountered in the treatment of congenital pulmonic stenosis.
• Surgical treatment of pulmonic stenosis.
• The chemotherapy of leukemia.
• The structured interview and interviewer training in the admissions process.
• The surgical treatment of congenital pulmonic stenosis.
• [Not Available.]
• [Not Available.]
• [Recent advances in cardiovascular surgery.]