Metabolic adaptations during the neonatal period in infants of diabetic mothers.

Metabolic adaptations during the neonatal period in infants of diabetic mothers. Research Abstract Details 

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Metabolic adaptations during the neonatal period in infants of diabetic mothers. Abstract Text:

J Hertel,C Kühl,

Infants of diabetic mothers (IDM's) are prone to develop severe but usually asymptomatic hypoglycaemia during the first postnatal hours. High maternal plasma glucose concentrations at the time of delivery increase this risk, especially if the mode of delivery is cesarean section. Newborn IDM's are hyperinsulinaemic and the neonatal hypoglycaemia seems to result from this together with a retarded increase in plasma glucagon levels. Despite very high plasma insulin concentrations, lipolysis, as indicated by a rise in plasma glycerol concentrations, appears to be normal in IDM's. The IDM's are able to respond to both physiologic and metabolic stress with an increased catecholamine secretion during the first hours of life, and the catecholamines seem to counteract the inhibitory effect of insulin on lipolysis and, at least partly, to oppose the blood glucose lowering effect of insulin.

Metabolic adaptations during the neonatal period in infants of diabetic mothers. Publishing Authors By Initials

J Hertel,C Kühl,

For similar female urogenital diseases and pregnancy complications: pregnancy complications: prenatal injuries: prenatal exposure delayed effects research abstracts see: female urogenital diseases and pregnancy complications: pregnancy complications: prenatal injuries: prenatal exposure delayed effects research

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Metabolic adaptations during the neonatal period in infants of diabetic mothers. Journal Published:

PUBLICATION TYPE: Review

Journal: Acta endocrinologica. Supplementum

VOLUME: 277

Page Numbers: 136-40

Journal Abbreviation:

ISSN: 0300-9750

DAY: 12

MONTH: 02

YEAR: 1986

Metabolic adaptations during the neonatal period in infants of diabetic mothers. Information

Number of References: 10

LANGUAGE: eng

NlmUniqueID: 370313

Metabolic adaptations during the neonatal period in infants of diabetic mothers. Keywords Mesh Terms:

KEYWORDS: Prenatal Exposure Delayed Effects

MESH TERMS: complications

Chemical & Substance for Abstract: Metabolic adaptations during the neonatal period in infants of diabetic mothers. Information

Substance Name: Glucagon

Registry Number: 9007-92-5

Grant and Affiliation Information for Metabolic adaptations during the neonatal period in infants of diabetic mothers.

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Country: DENMARK

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MEDLINETA: Acta Endocrinol Suppl (Copenh)

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