Metabolic activation and toxicology - some models of chemical protection against drug toxicity.

Metabolic activation and toxicology - some models of chemical protection against drug toxicity. Research Abstract Details 

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Metabolic activation and toxicology - some models of chemical protection against drug toxicity. Abstract Text:

This article describes some examples concerning the mechanism involved in the drug toxicity mediated by the enzymes of metabolism. They concern the production of various reactive metabolites which strongly bind to biological macromolecules inducing different forms of toxicity (necrosis, mutations and cancers). Some recent data on the field of protection and prevention means against the hepatoxicity of carcinogenesis are described.

Metabolic activation and toxicology - some models of chemical protection against drug toxicity. Publishing Authors By Initials

For similar polycyclic compounds research abstracts see: polycyclic compounds research

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MEDLINE DATE:

Metabolic activation and toxicology - some models of chemical protection against drug toxicity. Journal Published:

PUBLICATION TYPE: Review

Journal: Toxicological European research. Recherche europée

VOLUME: 3

Page Numbers: 161-6

Journal Abbreviation:

ISSN: 0249-6402

DAY: 26

MONTH: May

YEAR: 1981

Metabolic activation and toxicology - some models of chemical protection against drug toxicity. Information

Number of References: 26

LANGUAGE: eng

NlmUniqueID: 7901212

Metabolic activation and toxicology - some models of chemical protection against drug toxicity. Keywords Mesh Terms:

KEYWORDS: Polycyclic Compounds

MESH TERMS: toxicity

Chemical & Substance for Abstract: Metabolic activation and toxicology - some models of chemical protection against drug toxicity. Information

Substance Name: Cytochrome P-450 Enzyme System

Registry Number: 9035-51-2

Grant and Affiliation Information for Metabolic activation and toxicology - some models of chemical protection against drug toxicity.

AFFILIATION:

Country: FRANCE

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MEDLINETA: Toxicol Eur Res

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