Meta-Analysis of Neuropsychological Symptoms of Adolescents and Adults with PKU.

Meta-Analysis of Neuropsychological Symptoms of Adolescents and Adults with PKU. Research Abstract Details 

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Meta-Analysis of Neuropsychological Symptoms of Adolescents and Adults with PKU. Abstract Text:

J J Moyle,A M Fox,M Arthur,M Bynevelt,J R Burnett,

Phenylketonuria (PKU; OMIM 261600) is an autosomal recessive inborn error of phenylanaline metabolism. PKU is characterized by deficient or defective phenylalanine hydroxylase activity and persistantly increased levels of the essential amino acid phenylalanine in the circulation. The present article examines current understanding of the etiology of PKU, along with a meta-analysis examining neuropsychological and intellectual presentations in continuously treated adolescents and adults. Patients with PKU differed significantly from controls on Full-Scale IQ, processing speed, attention, inhibition, and motor control. Future research utilizing an integrative approach and detailed analysis of specific cognitive domains will assist both the scientist and clinician, and ultimately the patient.

Meta-Analysis of Neuropsychological Symptoms of Adolescents and Adults with PKU. Publishing Authors By Initials

JJ Moyle,AM Fox,M Arthur,M Bynevelt,JR Burnett,

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Meta-Analysis of Neuropsychological Symptoms of Adolescents and Adults with PKU. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Neuropsychology review

VOLUME: 17

Page Numbers: 91-101

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ISSN: 1040-7308

DAY: 5

MONTH: 04

YEAR: 2007

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LANGUAGE: eng

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AFFILIATION: School of Psychology, The University of Western Australia, Perth, Australia.

Country: United States

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MEDLINETA: Neuropsychol Rev

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