Menière's disease and autoimmunity: clinical study and survey.

Menière's disease and autoimmunity: clinical study and survey. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Menière's disease and autoimmunity: clinical study and survey. Abstract Text:

K Tomoda,Y Suzuka,H Iwai,T Yamashita,T Kumazawa,

In order to clarify whether autoimmune mechanisms form part of the etiopathogenesis of Meniere's disease, sera and endolymphatic sac tissues from 30 patients with Meniere's disease were analyzed according to the clinical criteria for autoimmune diseases stated by Mackay & Burnet. Several cases showed hyper gamma-globulinemia, antibody elevation to Type II collagen in the serum and endolymph, positive staining to immunoglobulins and C3 or infiltration of immuno-competent cells in the endolymphatic sac, good response to prednisolone and combination with systemic immune disorders. Other examinations showed a significant elevation of OKT 4/8 ratio and a decrease of OKT8-positive cells, and elevated levels of circulating immune complex and antiviral antibody titers. It is suggested that certain cases of Meniere's disease may have an altered immunological background, which may be attributed to an autoimmune mechanism dependent on humoral and/or cellular responses.

Menière's disease and autoimmunity: clinical study and survey. Publishing Authors By Initials

K Tomoda,Y Suzuka,H Iwai,T Yamashita,T Kumazawa,

For similar polycyclic compounds: steroids: pregnanes: pregnadienes: pregnadienetriols: prednisolone research abstracts see: polycyclic compounds: steroids: pregnanes: pregnadienes: pregnadienetriols: prednisolone research

PUBMED ID PMID:

MEDLINE DATE:

Menière's disease and autoimmunity: clinical study and survey. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta oto-laryngologica. Supplementum

VOLUME: 500

Page Numbers: 31-4

Journal Abbreviation:

ISSN: 0365-5237

DAY: 13

MONTH: 02

YEAR: 1993

Menière's disease and autoimmunity: clinical study and survey. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 370355

Menière's disease and autoimmunity: clinical study and survey. Keywords Mesh Terms:

KEYWORDS: Prednisolone

MESH TERMS: therapeutic use

Chemical & Substance for Abstract: Menière's disease and autoimmunity: clinical study and survey. Information

Substance Name: Collagen

Registry Number: 9007-34-5

Grant and Affiliation Information for Menière's disease and autoimmunity: clinical study and survey.

AFFILIATION: Department of Otorhinolaryngology, Kansai Medical University, Osaka, Japan.

Country: SWEDEN

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Acta Otolaryngol Suppl

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Menière's disease and autoimmunity: clinical study and survey Related Publications

• A possible masking effect of tinnitus. Evaluation of CNV audiometry.
• Active opening function of the human eustachian tube: comparison between sonotubometry and pressure equilibration test.
• Approach to the diagnosis of sialadenosis using sialography.
• Autonomic nervous system in human palatine tonsil.
• Effects of acetazolamide on acid-base balance in the endolymphatic sac of the guinea pig.
• Effects of efferent neurotransmitters on intracellular Ca2+ concentration in vestibular hair cells of the guinea pig.
• Effects of miglitol, an alpha-glucosidase inhibitor, on glycaemic status and histopathological changes in islets in non-obese, non-insulin-dependent diabetic Goto-Kakizaki rats.
• Enhanced parasympathetic nerve activities in experimentally-induced nasal hypersensitivity.
• Establishment of a cisplatin-resistant KB cell line and its characterization.
• Experimental and clinical evaluation of DNA ploidy with use of double staining of keratin/DNA by flow cytometer in head and neck tumor.
• Functional disturbances of the sympathetic nerve in experimentally-induced nasal hypersensitivity.
• Head and neck reconstruction with microvascular tissue transfer and its surgical indications: our experiences. A review.
• Histamine and acetylcholine regulation of sympathetic nerve activity in guinea-pig nasal mucosa.
• Histamine content and histamine H1 receptor in experimentally-induced nasal hypersensitivity.
• Kinetics of epidermal growth factor in saliva.
• Menière's disease and autoimmunity: clinical study and survey.
• Middle ear ventilation mechanism.
• Molecular phylogenetic and dating analyses using mitochondrial DNA sequences of eyelid geckos (Squamata: Eublepharidae).
• Norepinephrine content in guinea-pig nasal mucosa response to histamine and methacholine provocation.
• Otitis media with effusion and eustachian tube dysfunction in adults and children.
• Otitis media with effusion and tubal tonsil (video).
• Participation of autonomic nerve in tonsillar focal infection.
• Recent activities in otolaryngology -- head and neck surgery. Dedicated to Professor Tadami Kumazawa.
• Regulation of Cl- conductance in delayed shortening and shrinkage of outer hair cells.
• Subjective results of laser surgery for allergic rhinitis.
• Surgical anatomy for infralabyrinthine approach to the internal auditory canal.
• The tonsillar immune system: its response to exogenous antigens.
• The usefulness of partial parotidectomy for benign parotid gland tumors. A retrospective study of 306 cases.
• Thermal influence on intracellular calcium concentration in vestibular hair cells isolated from the guinea pig. A preliminary report.
• Thyroid follicle transplantation by percutaneous injection.