Membrane biosensor platforms using nano- and microporous supports.

Membrane biosensor platforms using nano- and microporous supports. Research Abstract Details 

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Membrane biosensor platforms using nano- and microporous supports. Abstract Text:

Erik Reimhult,Karthik Kumar,

Lipid membranes are versatile and convenient models for the study of properties of natural cell membranes. In particular, surface-supported membranes have attracted considerable attention because the whole range of surface-sensitive techniques, including interface-sensitive electrochemical measurements, can be used with them. Here we describe recent advances and current directions in the development of nano- and microporous substrates for electrochemical characterization of membrane protein-containing lipid bilayers. Improved techniques for lipid membrane self-assembly and membrane protein incorporation on these substrates have led to great improvements in measurement sensitivity, membrane stability and packaging. These advances suggest that nanopore-spanning membranes are leading contenders for a breakthrough in membrane protein screening and biosensing applications.

Membrane biosensor platforms using nano- and microporous supports. Publishing Authors By Initials

E Reimhult,K Kumar,

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Membrane biosensor platforms using nano- and microporous supports. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Trends in biotechnology

VOLUME: 26

Page Numbers: 82-9

Journal Abbreviation: Trends Biotechnol.

ISSN: 0167-7799

DAY: 11

MONTH: 01

YEAR: 2008

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LANGUAGE: eng

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AFFILIATION: Swiss Federal Institute of Technology Zurich (Eidgenössische Technische Hochschule Zürich, ETHZ), Laboratory for Surface Science and Technology, BioInterfaceGroup, Wolgang-Pauli-Strasse 10, CH-8093 Zurich, Switzerland.

Country: England

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MEDLINETA: Trends Biotechnol

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