Meeting Report: Receptor tyrosine kinases: the emerging tip of systems control.

Meeting Report: Receptor tyrosine kinases: the emerging tip of systems control. Research Abstract Details 

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Meeting Report: Receptor tyrosine kinases: the emerging tip of systems control. Abstract Text:

R Seger,U Rodeck,Y Yarden,R Seger,U Rodeck,Y Yarden,

Receptor tyrosine kinases (RTKs) are transmembrane allosteric enzymes: binding of ligand growth factors to their ectodomains stimulates a cytoplasm-facing tyrosine kinase activity, which initiates a plethora of cellular processes. The enormous complexity of RTK signalling, along with rich involvement in pathologies (e.g. cancer and diabetes), motivated the establishment of the international, multi-disciplinary RTK consortium (http://www.rtkconsort.org/) in 2005. In collaboration with the British Society for Proteome Research and the European Bioinformatics Institute, the Consortium held on July 23rd and 24th a Workshop on Proteomics and Phosphoproteomics of RTK Signalling Networks (Hinxton Hall Conference Centre, Cambridge, UK). As highlighted below, systems control (a layered web of regulatory loops summarised in Fig.1) emerged throughout the workshop as a common theme of many presentations.

Meeting Report: Receptor tyrosine kinases: the emerging tip of systems control. Publishing Authors By Initials

R Seger,U Rodeck,Y Yarden,R Seger,U Rodeck,Y Yarden,

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Meeting Report: Receptor tyrosine kinases: the emerging tip of systems control. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: IET systems biology

VOLUME: 2

Page Numbers: 1

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ISSN: 1751-8849

DAY: 5

MONTH: Jan

YEAR: 2008

Meeting Report: Receptor tyrosine kinases: the emerging tip of systems control. Information

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LANGUAGE: eng

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AFFILIATION: Weizmann Institute of Science, Department of Biological Regulation, Rehovot, IsraelThomas Jefferson University, Department of Dermatology and Cutaneous Biology, Philadelphia, USA.

Country: England

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MEDLINETA: IET Syst Biol

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