Medical conditions increasing the risk of chronic thromboembolic pulmonary hypertension.

Medical conditions increasing the risk of chronic thromboembolic pulmonary hypertension. Research Abstract Details 

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Medical conditions increasing the risk of chronic thromboembolic pulmonary hypertension. Abstract Text:

Diana Bonderman,Johannes Jakowitsch,Christopher Adlbrecht,Michael Schemper,Paul A Kyrle,Verena ,Markus Exner,Walter Klepetko,Meinhard P Kneussl,Gerald Maurer,Irene Lang,

Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by organized thromboemboli that obstruct the pulmonary vascular bed. Although CTEPH is a serious complication of acute symptomatic pulmonary embolism in 4% of cases, signs, symptoms and classical risk factors for venous thromboembolism are lacking. The aim of the present study was to identify medical conditions conferring an increased risk of CTEPH. We performed a case-control-study comparing 109 consecutive CTEPH patients to 187 patients with acute pulmonary embolism that was confirmed by a high probability lung scan. Splenectomy (odds ratio=13, 95% CI 2.7-127), ventriculo-atrial (VA-) shunt for the treatment of hydrocephalus (odds ratio=13, 95% CI 2.5-129) and chronic inflammatory disorders, such as osteomyelitis and inflammatory bowel disease (IBD, odds ratio=67, 95% CI 7.9-8832) were associated with an increased risk of CTEPH.

Medical conditions increasing the risk of chronic thromboembolic pulmonary hypertension. Publishing Authors By Initials

D Bonderman,J Jakowitsch,C Adlbrecht,M Schemper,PA Kyrle,V ,M Exner,W Klepetko,MP Kneussl,G Maurer,I Lang,

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Medical conditions increasing the risk of chronic thromboembolic pulmonary hypertension. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Thrombosis and haemostasis

VOLUME: 93

Page Numbers: 512-6

Journal Abbreviation: Thromb. Haemost.

ISSN: 0340-6245

DAY: 28

MONTH: Mar

YEAR: 2005

Medical conditions increasing the risk of chronic thromboembolic pulmonary hypertension. Information

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LANGUAGE: eng

NlmUniqueID: 7608063

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Grant and Affiliation Information for Medical conditions increasing the risk of chronic thromboembolic pulmonary hypertension.

AFFILIATION: Medical University of Vienna, Department of Cardiology, Vienna, Austria.

Country: Germany

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MEDLINETA: Thromb Haemost

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