Mechanisms of tolerance induced via mixed chimerism.

Mechanisms of tolerance induced via mixed chimerism. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Mechanisms of tolerance induced via mixed chimerism. Abstract Text:

Megan Sykes,

Mixed hematopoietic chimerism provides a powerful means of inducing robust, donor-specific tolerance. In this article, the minimal requirements for achieving mixed chimerism, the development of new reagents that promote its achievement, and the mechanisms by which peripheral and intrathymic tolerance are achieved via mixed chimerism are discussed. An emerging understanding of these mechanisms, along with the development of new immunosuppressive reagents, is allowing advancement toward clinical application of this approach.

Mechanisms of tolerance induced via mixed chimerism. Publishing Authors By Initials

M Sykes,

For similar biological phenomena, cell phenomena, and immunity: immunity: immune tolerance research abstracts see: biological phenomena, cell phenomena, and immunity: immunity: immune tolerance research

PUBMED ID PMID:

MEDLINE DATE:

Mechanisms of tolerance induced via mixed chimerism. Journal Published:

PUBLICATION TYPE: Review

Journal: Frontiers in bioscience : a journal and virtual li

VOLUME: 12

Page Numbers: 2922-34

Journal Abbreviation:

ISSN: 1093-4715

DAY: 1

MONTH: 05

YEAR: 2007

Mechanisms of tolerance induced via mixed chimerism. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9709506

Mechanisms of tolerance induced via mixed chimerism. Keywords Mesh Terms:

KEYWORDS: Immune Tolerance

MESH TERMS: immunology

Chemical & Substance for Abstract: Mechanisms of tolerance induced via mixed chimerism. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Mechanisms of tolerance induced via mixed chimerism.

AFFILIATION: Transplantation Biology Research Center, Department of Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, MA 02129, USA. Megan.Sykes@tbrc.mgh.harvard.edu

Country: United States

AGENCY: United States NHLBI

GRANT: R01 HL49915

ACRONYM: HL

MEDLINETA: Front Biosci

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Mechanisms of tolerance induced via mixed chimerism Related Publications

• ARF1-mediated actin polymerization produces movement of artificial vesicles.
• Advances in scalp reconstruction.
• Aesthetic correction of chin deformities-bony genioplasty.
• And so to Boston (1954-1955).
• B-cell extrinsic CR1/CR2 promotes natural antibody production and tolerance induction of anti-alphaGAL-producing B-1 cells.
• Bs20 familial gynaecological cancer - aspects of clinical management.
• Effects of pacatal on symptoms in chronic psychotic female in-patients.
• GalT-KO pigs: is the cup half empty or half full?
• Geologic constraints on clandestine nuclear testing in South Asia.
• Immune tolerance: mechanisms and application in clinical transplantation.
• Manipulating host immunity to improve nematode parasite control -Quo vadit.
• Mechanisms of tolerance induced via mixed chimerism.
• Methyl n-propyl ether.
• Modulation of Cardiac Troponin C Function by the Cardiac-Specific N-Terminus of Troponin I: Influence of PKA Phosphorylation and Involvement in Cardiomyopathies.
• NK cell tolerance in mixed allogeneic chimeras.
• NMR studies of the dynamics of a bifunctional rhodamine probe attached to troponin C.
• Nuclear magnetic resonance studies of CXC chemokine receptor 4 allosteric peptide agonists in solution.
• Obstruction of the superior vena cava; a review of the literature and report of two personal cases.
• Porcine thymic grafts protect human thymocytes from HIV-1-induced destruction.
• Regulatory T-cell recovery in recipients of haploidentical nonmyeloablative hematopoietic cell transplantation with a humanized anti-CD2 mAb, MEDI-507, with or without fludarabine.
• Role of emotion in glaucoma.
• Shape-tunable polymer nodules grown from liposomes via ring-opening metathesis polymerization.
• Speech privacy in healthcare facilities.
• St Christopher's and the future.
• The nurse in industry.
• The quality of public dialogue.
• The role of antigen-presenting cells in triggering graft-versus-host disease and graft-versus-leukemia.
• The styloid-stylohyoid syndrome: review of the literature and case report.
• Tryptophan Mutants of Cardiac Troponin C: 3D Structure, Troponin I Affinity, and in Situ Activity(,).
• [Plan for modernization of a neurosurgery unit in a modern hospital wing in England.]