Mechanism of DNA transport through pores.

Mechanism of DNA transport through pores. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Mechanism of DNA transport through pores. Abstract Text:

Murugappan Muthukumar,

The transport of electrically charged macromolecules such as DNA through narrow pores is a fundamental process in life. When polymer molecules are forced to navigate through pores, their transport is controlled by entropic barriers that accompany their conformational changes. During the past decade, exciting results have emerged from single-molecule electrophysiology experiments. Specifically, the passage of single-stranded DNA/RNA through alpha-hemolysin pores and double-stranded DNA through solid-state nanopores has been investigated. By a combination of these results with the entropic barrier theory of polymer transport and macromolecular simulations, an understanding of the mechanism of DNA transport through pores has emerged.

Mechanism of DNA transport through pores. Publishing Authors By Initials

M Muthukumar,

For similar natural sciences: physics: thermodynamics research abstracts see: natural sciences: physics: thermodynamics research

PUBMED ID PMID:

MEDLINE DATE:

Mechanism of DNA transport through pores. Journal Published:

PUBLICATION TYPE: Review

Journal: Annual review of biophysics and biomolecular struc

VOLUME: 36

Page Numbers: 435-50

Journal Abbreviation:

ISSN: 1056-8700

DAY: 3

MONTH: 12

YEAR: 2007

Mechanism of DNA transport through pores. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9211097

Mechanism of DNA transport through pores. Keywords Mesh Terms:

KEYWORDS: Thermodynamics

MESH TERMS: metabolism

Chemical & Substance for Abstract: Mechanism of DNA transport through pores. Information

Substance Name: DNA

Registry Number: 9007-49-2

Grant and Affiliation Information for Mechanism of DNA transport through pores.

AFFILIATION: Polymer Science and Engineering Department, University of Massachusetts, Amherst, Massachusetts 01003, USA. muthu@polysci.umass.edu

Country: United States

AGENCY: United States NHGRI

GRANT: 1R01HG002776-01

ACRONYM: HG

MEDLINETA: Annu Rev Biophys Biomol Struct

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Mechanism of DNA transport through pores Related Publications

• An overview of enzymatic production of biodiesel.
• Cerebral venous sinus thrombosis and thrombophilia presenting as pseudo-tumour syndrome following mild head injury.
• Chain entropy: spoiler or benefactor in pattern recognition?
• Confinement free energy of flexible polyelectrolytes in spherical cavities.
• Electrostatic origin of the genome packing in viruses.
• Entropy and enthalpy of polyelectrolyte complexation: Langevin dynamics simulations.
• Langevin dynamics simulations of ds-DNA translocation through synthetic nanopores.
• Mechanism of DNA transport through pores.
• Phase separation kinetics of polyelectrolyte solutions.
• Polymer capture by electro-osmotic flow of oppositely charged nanopores.
• Polymer translocation through a cylindrical channel.
• Scaling theory of polymer translocation into confined regions.
• Theory of competitive counterion adsorption on flexible polyelectrolytes: Divalent salts.
• Theory of counter-ion condensation on flexible polyelectrolytes: adsorption mechanism.