Mechanism by which Bombyx mori hemocytes recognize microorganisms: direct and indirect recognition systems for PAMPs.

Mechanism by which Bombyx mori hemocytes recognize microorganisms: direct and indirect recognition systems for PAMPs. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Mechanism by which Bombyx mori hemocytes recognize microorganisms: direct and indirect recognition systems for PAMPs. Abstract Text:

Masayuki Ohta,Ayako Watanabe,Tetsuo Mikami,Yuichi Nakajima,Madoka Kitami,Hiroko Tabunoki,Kenjirou Ueda,Ryoichi Sato,Masayuki Ohta,Ayako Watanabe,Tetsuo Mikami,Yuichi Nakajima,Madoka Kitami,Hiroko Tabunoki,Kenjirou Ueda,Ryoichi Sato,

Hemocytes play an important role in cellular reactions in the immune system. Although the recognition of pathogens is thought to involve pattern-recognition proteins (PRPs) in insects, the exact mechanisms by which insect hemocytes recognize pathogens are not clear. This study examined the mechanism by which Bombyx mori hemocytes recognize microorganisms and pathogen-associated molecular patterns (PAMPs) using flow cytometry and fluorescence microscopy. Fluorescence-labeled bacterial or fungal cells were observed to bind to hemocytes and this binding was inhibited by adding lipoteichoic acid (LTA) or beta-1,3-glucan. Lipopolysaccharide (LPS) bound to hemocytes directly. These results suggest that hemocytes have a mechanism that recognizes LPS, LTA, and beta-1,3-glucan directly. Previously, we identified two types of C-type lectin (BmLBP and BmMBP) and showed that they recognize a variety of PAMPs leading to the induction of nodule formation. These lectins enhanced hemocyte binding to microorganisms and their direct binding to hemocytes suggests that hemocytes have a mechanism for recognizing microorganisms using lectin receptors.

Mechanism by which Bombyx mori hemocytes recognize microorganisms: direct and indirect recognition systems for PAMPs. Publishing Authors By Initials

M Ohta,A Watanabe,T Mikami,Y Nakajima,M Kitami,H Tabunoki,K Ueda,R Sato,M Ohta,A Watanabe,T Mikami,Y Nakajima,M Kitami,H Tabunoki,K Ueda,R Sato,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Mechanism by which Bombyx mori hemocytes recognize microorganisms: direct and indirect recognition systems for PAMPs. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Developmental and comparative immunology

VOLUME: 30

Page Numbers: 867-77

Journal Abbreviation:

ISSN: 0145-305X

DAY: 10

MONTH: 01

YEAR: 2006

Mechanism by which Bombyx mori hemocytes recognize microorganisms: direct and indirect recognition systems for PAMPs. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7708205

Mechanism by which Bombyx mori hemocytes recognize microorganisms: direct and indirect recognition systems for PAMPs. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Mechanism by which Bombyx mori hemocytes recognize microorganisms: direct and indirect recognition systems for PAMPs. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Mechanism by which Bombyx mori hemocytes recognize microorganisms: direct and indirect recognition systems for PAMPs.

AFFILIATION: Tokyo University of Agriculture and Technology, Naka-cho 2-24-16, Koganei, Tokyo 184-8588, Japan.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Dev Comp Immunol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Mechanism by which Bombyx mori hemocytes recognize microorganisms: direct and indirect recognition systems for PAMPs Related Publications

• Age related changes in the distribution of laryngeal glands in the human adult larynx.
• Anti-eosinophil peroxidase antibodies detected in patients with primary biliary cirrhosis.
• Assessment of bull fertility using a mucus penetration test and a human chorionic gonadotrophin stimulation test.
• Colonic mucosal lesions associated with long-term administration of non-steroidal anti-inflammatory drugs.
• Decreased expression levels of CD22 and L-selectin on peripheral blood B lymphocytes from patients with bullous pemphigoid.
• Differences in acetazolamide vasoreactivity in patients with acute and chronic occlusion of the internal carotid artery.
• Effect of low-molecular-weight heparin on the commitment of bone marrow cells to liver sinusoidal endothelial cells in CCl(4)-induced liver injury.
• Effects of gonadotropin releasing hormone and prostaglandin F(2)alpha on the reproductive performance in postpartum cows.
• Exacerbation of dietary steatohepatitis and fibrosis in obese, diabetic KK-A(y) mice.
• Expression of MUC1 and MUC2 mucin antigens in intrahepatic bile duct tumors: its relationship with a new morphological classification of cholangiocarcinoma.
• Expression of MUC1 and MUC2 mucins in gastric carcinomas: its relationship with the prognosis of the patients.
• Expression of mucin antigens in human cancers and its relationship with malignancy potential.
• Gene expression of gastric type mucin (MUC5AC) in pancreatic tumors: its relationship with the biological behavior of the tumor.
• Hepatic steatosis is a predictor of poor response to interferon alpha-2b and ribavirin combination therapy in Japanese patients with chronic hepatitis C.
• Immunohistochemical study of mucin carbohydrates and core proteins in human pancreatic tumors.
• Infective Endocarditis Associated with Sjogren's Syndrome.
• Isokinetic external rotation strength of shoulder : correlation with age and muscle size.
• MUC-1 mucin expression in invasive areas of intraductal papillary mucinous tumors of the pancreas.
• MUC2 gene expression is found in noninvasive tumors but not in invasive tumors of the pancreas and liver: its close relationship with prognosis of the patients.
• Mechanism by which Bombyx mori hemocytes recognize microorganisms: direct and indirect recognition systems for PAMPs.
• Modeling of daily operation in proton radiotherapy by Monte Carlo method.
• Mucin antigen expression in gastric carcinomas of young and old adults.
• Prostaglandin E(2) levels in uterine tissues and its relationship with uterine and luteal progesterone during the estrous cycle in dairy cows.
• Reconstruction of scalp and cranium defect utilizing latissimus dorsi musculocutaneous and serratus anterior muscle free flaps with interpositional anastomosis of T-shaped flap artery: case report.
• Second messenger systems mediating sex pheromone and amino Acid sensitivity in goldfish olfactory receptor neurons.
• Study on the appearance of the cavity in the corpus luteum of cows by using ultrasonic scanning.
• The expression of several types of mucin is related to the biological behavior of pancreatic neoplasms.
• The role of leptin in progression of non-alcoholic fatty liver disease.
• Voglibose potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen by inducing CYP2E1 in rats.
• [Development and operation of cultured cell experiment with TR-IA sounding rocket]