Measuring fatigue for children with cancer: development and validation of the pediatric Functional Assessment of Chronic Illness Therapy-Fatigue (pedsFACIT-F).

Measuring fatigue for children with cancer: development and validation of the pediatric Functional Assessment of Chronic Illness Therapy-Fatigue (pedsFACIT-F). Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Measuring fatigue for children with cancer: development and validation of the pediatric Functional Assessment of Chronic Illness Therapy-Fatigue (pedsFACIT-F). Abstract Text:

Jin-Shei Lai,David Cella,Mary Jo Kupst,Suzanne Holm,Michael E Kelly,Rita K Bode,Stewart Goldman,

Fatigue is a major concern for cancer patients of all ages. The lack of an appropriate assessment tool has impeded our understanding of its prevalence and significance, specifically in the pediatric cancer population. This paper documents the reliability and validity of the pediatric Functional Assessment of Chronic Illness Therapy-Fatigue (pedsFACIT-F) in a comprehensive manner. The 11-item PedsFACIT-F was developed via literature review, feedback from patient/parent/clinician, and a face-to-face consensus meeting. Its reliability and validity were examined on the basis of data from 159 pediatric patients with cancer via classical test theory and Rasch analysis. Results showed that the pedsFACIT-F demonstrated good internal consistency (Cronbach alpha), acceptable item-total correlations, and met the unidimensionality assumption set by confirmatory factor analysis. All items had acceptable fit statistics in the Rasch analysis and demonstrated stable measurement properties by age, sex, and cancer type. Scores on the pedsFACIT-F significantly discriminated between patients with and without anemia and among patients with different functional status; clinically relevant minimally important differences were estimated accordingly. The pedsFACIT-F was significantly correlated to the PedsQL Multidimensional Fatigue Scale. In conclusion, the pedsFACIT-F demonstrates satisfactory reliability and validity and can be a useful tool in clinical trials and other research.

Measuring fatigue for children with cancer: development and validation of the pediatric Functional Assessment of Chronic Illness Therapy-Fatigue (pedsFACIT-F). Publishing Authors By Initials

JS Lai,D Cella,MJ Kupst,S Holm,ME Kelly,RK Bode,S Goldman,

For similar neoplasms research abstracts see: neoplasms research

PUBMED ID PMID:

MEDLINE DATE:

Measuring fatigue for children with cancer: development and validation of the pediatric Functional Assessment of Chronic Illness Therapy-Fatigue (pedsFACIT-F). Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of pediatric hematology/oncology : officia

VOLUME: 29

Page Numbers: 471-9

Journal Abbreviation: J. Pediatr. Hematol. Oncol.

ISSN: 1077-4114

DAY: 3

MONTH: Jul

YEAR: 2007

Measuring fatigue for children with cancer: development and validation of the pediatric Functional Assessment of Chronic Illness Therapy-Fatigue (pedsFACIT-F). Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9505928

Measuring fatigue for children with cancer: development and validation of the pediatric Functional Assessment of Chronic Illness Therapy-Fatigue (pedsFACIT-F). Keywords Mesh Terms:

KEYWORDS: Neoplasms

MESH TERMS: complications

Chemical & Substance for Abstract: Measuring fatigue for children with cancer: development and validation of the pediatric Functional Assessment of Chronic Illness Therapy-Fatigue (pedsFACIT-F). Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Measuring fatigue for children with cancer: development and validation of the pediatric Functional Assessment of Chronic Illness Therapy-Fatigue (pedsFACIT-F).

AFFILIATION: Center on Outcomes, Research and Education (CORE), Evanston Northwestern Healthcare, Evanston, IL 60201, USA. js-lai@northwestern.edu

Country: United States

AGENCY: United States NCI

GRANT: R21 CA10894-01

ACRONYM: CA

MEDLINETA: J Pediatr Hematol Oncol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Measuring fatigue for children with cancer: development and validation of the pediatric Functional Assessment of Chronic Illness Therapy-Fatigue pedsFACIT-F Related Publications

• A two-center, double-blinded, randomized trial testing the tolerability and efficacy of a novel therapeutic agent for cellulite reduction.
• Activity-dependent gene regulation in skeletal muscle is mediated by a histone deacetylase (HDAC)-Dach2-myogenin signal transduction cascade.
• An alpha-(1,4)-amylase is essential for alpha-(1,3)-glucan production and virulence in Histoplasma capsulatum.
• An integrated approach to the management of chronic myeloid leukemia.
• Cardiac concussion (commotio cordis).
• Classification of Impulse Oscillometric Patterns of Lung Function in Asthmatic Children using Artificial Neural Networks.
• Commentary: a case for minimizing folate supplementation in clinical regimens with pemetrexed based on the marked sensitivity of the drug to folate availability.
• Defining virulence genes in the dimorphic fungi.
• Do biomarkers of stress mediate the relation between socioeconomic status and health?
• Dorsal radial glia generate olfactory bulb interneurons in the postnatal murine brain.
• Evaluation of respiratory system models based on parameter estimates from impulse oscillometry data.
• Experimental design criteria in phylogenetics: where to add taxa.
• Glial progenitor-based repair of demyelinating neurological diseases.
• Histoplasma capsulatum alpha-(1,3)-glucan blocks innate immune recognition by the beta-glucan receptor.
• Intravascular lasers in the treatment of varicose veins.
• Measuring fatigue for children with cancer: development and validation of the pediatric Functional Assessment of Chronic Illness Therapy-Fatigue (pedsFACIT-F).
• Modeling human respiratory impedance. Comparing the best method with the least estimation errors.
• Neurocytoma is a tumor of adult neuronal progenitor cells.
• Parasitic infections of the skin.
• Peak selection from MALDI-TOF mass spectra using ant colony optimization.
• Renal disease in an antiretroviral-naïve HIV-infected outpatient population in Western Kenya.
• Risk factors for physical assault and rape among six Native American tribes.
• Saliva from subjects harboring Actinobacillus actinomycetemcomitans kills Streptococcus mutans in vitro.
• Selection of cholera toxin specific IgNAR single-domain antibodies from a naïve shark library.
• Serologic evidence for regional differences in pediatric cryptococcal infection.
• Synergistic effects of the SAPK/JNK and the proteasome pathway on glial fibrillary acidic protein (GFAP) accumulation in Alexander disease.
• The effect of a novel transition state inhibitor of methylthioadenosine phosphorylase on pemetrexed activity.
• Using Q-methodology to understand perceived fatigue reported by adolescents with cancer.
• Using ancestry-informative markers to define populations and detect population stratification.
• Women's Health Initiative Perspective: What Does It Really Mean to the Rheumatologist?