Mayo clinic risk score for percutaneous coronary intervention predicts in-hospital mortality in patients undergoing coronary artery bypass graft surgery.

Mayo clinic risk score for percutaneous coronary intervention predicts in-hospital mortality in patients undergoing coronary artery bypass graft surgery. Research Abstract Details 

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Mayo clinic risk score for percutaneous coronary intervention predicts in-hospital mortality in patients undergoing coronary artery bypass graft surgery. Abstract Text:

Mandeep Singh,Bernard J Gersh,Shuang Li,John S Rumsfeld,John A Spertus,Sean M O'Brien,Rakesh M Suri,Eric D Peterson,Mandeep Singh,Bernard J Gersh,Shuang Li,John S Rumsfeld,John A Spertus,Sean M O'Brien,Rakesh M Suri,Eric D Peterson,

BACKGROUND: Current risk models predict in-hospital mortality after either coronary artery bypass graft surgery or percutaneous coronary interventions separately, yet the overlap suggests that the same variables can define the risks of alternative coronary reperfusion therapies. Our goal was to seek a preprocedure risk model that can predict in-hospital mortality after either percutaneous coronary intervention or coronary artery bypass graft surgery. METHODS AND RESULTS: We tested the ability of the recently validated, integer-based Mayo Clinic Risk Score (MCRS) for percutaneous coronary intervention, which is based solely on preprocedure variables (age, creatinine, ejection fraction, myocardial infarction /=70 years old. A high prevalence of comorbid conditions, including diabetes mellitus (37.1%), hypertension (80.5%), peripheral vascular disease (15.3%), and renal disease (creatinine >/=1.4 mg/dL; 11.8%), was present. A strong association existed between the MCRS and the observed mortality in the Society of Thoracic Surgeons database. The in-hospital mortality ranged between 0.3% (95% confidence interval 0.3% to 0.4%) with a score of 0 on the MCRS and 33.8% (95% confidence interval 27.3% to 40.3%) with an MCRS score of 20 to 24. The discriminatory ability of the MCRS was moderate, as measured by the area under the receiver operating characteristic curve (C-statistic=0.715 to 0.784 among various subgroups); performance was inferior to the Society of Thoracic Surgeons model for most categories tested. CONCLUSIONS: This model, which is based on 7 preprocedure risk variables, may be useful for providing patients with individualized, evidence-based estimates of procedural risk as part of the informed consent process before percutaneous or surgical revascularization.

Mayo clinic risk score for percutaneous coronary intervention predicts in-hospital mortality in patients undergoing coronary artery bypass graft surgery. Publishing Authors By Initials

M Singh,BJ Gersh,S Li,JS Rumsfeld,JA Spertus,SM O'Brien,RM Suri,ED Peterson,M Singh,BJ Gersh,S Li,JS Rumsfeld,JA Spertus,SM O'Brien,RM Suri,ED Peterson,

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Mayo clinic risk score for percutaneous coronary intervention predicts in-hospital mortality in patients undergoing coronary artery bypass graft surgery. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Circulation

VOLUME: 117

Page Numbers: 356-62

Journal Abbreviation: Circulation

ISSN: 1524-4539

DAY: 2

MONTH: 01

YEAR: 2008

Mayo clinic risk score for percutaneous coronary intervention predicts in-hospital mortality in patients undergoing coronary artery bypass graft surgery. Information

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LANGUAGE: eng

NlmUniqueID: 147763

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Grant and Affiliation Information for Mayo clinic risk score for percutaneous coronary intervention predicts in-hospital mortality in patients undergoing coronary artery bypass graft surgery.

AFFILIATION: MPH, Division of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN 55905.

Country: United States

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MEDLINETA: Circulation

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