Matrices and scaffolds for drug delivery in dental, oral and craniofacial tissue engineering.

Matrices and scaffolds for drug delivery in dental, oral and craniofacial tissue engineering. Research Abstract Details 

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Matrices and scaffolds for drug delivery in dental, oral and craniofacial tissue engineering. Abstract Text:

Eduardo K Moioli,Paul A Clark,Xuejun Xin,Shan Lal,Jeremy J Mao,

Current treatments for diseases and trauma of dental, oral and craniofacial (DOC) structures rely on durable materials such as amalgam and synthetic materials, or autologous tissue grafts. A paradigm shift has taken place to utilize tissue engineering and drug delivery approaches towards the regeneration of these structures. Several prototypes of DOC structures have been regenerated such as temporomandibular joint (TMJ) condyle, cranial sutures, tooth structures and periodontium components. However, many challenges remain when taking in consideration the high demand for esthetics of DOC structures, the complex environment and yet minimal scar formation in the oral cavity, and the need for accommodating multiple tissue phenotypes. This review highlights recent advances in the regeneration of DOC structures, including the tooth, periodontium, TMJ, cranial sutures and implant dentistry, with specific emphasis on controlled release of signaling cues for stem cells, biomaterial matrices and scaffolds, and integrated tissue engineering approaches.

Matrices and scaffolds for drug delivery in dental, oral and craniofacial tissue engineering. Publishing Authors By Initials

EK Moioli,PA Clark,X Xin,S Lal,JJ Mao,

For similar stomatognathic diseases: tooth diseases research abstracts see: stomatognathic diseases: tooth diseases research

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MEDLINE DATE:

Matrices and scaffolds for drug delivery in dental, oral and craniofacial tissue engineering. Journal Published:

PUBLICATION TYPE: Review

Journal: Advanced drug delivery reviews

VOLUME: 59

Page Numbers: 308-24

Journal Abbreviation: Adv. Drug Deliv. Rev.

ISSN: 0169-409X

DAY: 18

MONTH: 04

YEAR: 2007

Matrices and scaffolds for drug delivery in dental, oral and craniofacial tissue engineering. Information

Number of References: 182

LANGUAGE: eng

NlmUniqueID: 8710523

Matrices and scaffolds for drug delivery in dental, oral and craniofacial tissue engineering. Keywords Mesh Terms:

KEYWORDS: Tooth Diseases

MESH TERMS: therapy

Chemical & Substance for Abstract: Matrices and scaffolds for drug delivery in dental, oral and craniofacial tissue engineering. Information

Substance Name: Intercellular Signaling Peptides and Pro

Registry Number: 0

Grant and Affiliation Information for Matrices and scaffolds for drug delivery in dental, oral and craniofacial tissue engineering.

AFFILIATION: Columbia University, Tissue Engineering and Regenerative Medicine Laboratory (TERML), College of Dental Medicine, Fu Foundation School of Engineering and Applied Sciences, Department of Biomedical Engineering, New York, NY 10032, USA.

Country: Netherlands

AGENCY: United States NIBIB

GRANT: EB02332

ACRONYM: EB

MEDLINETA: Adv Drug Deliv Rev

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