Maternal fish consumption, mercury levels, and risk of preterm delivery.

Maternal fish consumption, mercury levels, and risk of preterm delivery. Research Abstract Details 

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Maternal fish consumption, mercury levels, and risk of preterm delivery. Abstract Text:

Fei Xue,Claudia Holzman,Mohammad Hossein Rahbar,Kay Trosko,Lawrence Fischer,

BACKGROUND: Pregnant women receive mixed messages about fish consumption in pregnancy because unsaturated fatty acids and protein in fish are thought to be beneficial, but contaminants such as methylmercury may pose a hazard. METHODS: In the Pregnancy Outcomes and Community Health (POUCH) study, women were enrolled in the 15th to 27th week of pregnancy from 52 prenatal clinics in five Michigan communities. At enrollment, information was gathered on amount and category of fish consumed during the current pregnancy, and a hair sample was obtained. A segment of hair closest to the scalp, approximating exposure during pregnancy, was assessed for total mercury levels (70-90% methylmercury) in 1,024 POUCH cohort women. RESULTS: Mercury levels ranged from 0.01 to 2.50 pg/g (mean = 0.29 microg/g; median = 0.23 microg/g). Total fish consumption and consumption of canned fish, bought fish, and sport-caught fish were positively associated with mercury levels in hair. The greatest fish source for mercury exposure appeared to be canned fish. Compared with women delivering at term, women who delivered before 35 weeks' gestation were more likely to have hair mercury levels at or above the 90th percentile (> or = 0.55 microg/g), even after adjusting for maternal characteristics and fish consumption (adjusted odds ratio = 3.0; 95% confidence interval, 1.3-6.7). CONCLUSION: This is the first large, community-based study to examine risk of very preterm birth in relation to mercury levels among women with low to moderate exposure. Additional studies are needed to see whether these findings will be replicated in other settings.

Maternal fish consumption, mercury levels, and risk of preterm delivery. Publishing Authors By Initials

F Xue,C Holzman,MH Rahbar,K Trosko,L Fischer,

For similar chemical actions and uses: toxic actions: environmental pollutants: water pollutants: water pollutants, chemical research abstracts see: chemical actions and uses: toxic actions: environmental pollutants: water pollutants: water pollutants, chemical research

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Maternal fish consumption, mercury levels, and risk of preterm delivery. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Environmental health perspectives

VOLUME: 115

Page Numbers: 42-7

Journal Abbreviation: Environ. Health Perspect.

ISSN: 0091-6765

DAY: 3

MONTH: Jan

YEAR: 2007

Maternal fish consumption, mercury levels, and risk of preterm delivery. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 330411

Maternal fish consumption, mercury levels, and risk of preterm delivery. Keywords Mesh Terms:

KEYWORDS: Water Pollutants, Chemical

MESH TERMS: analysis

Chemical & Substance for Abstract: Maternal fish consumption, mercury levels, and risk of preterm delivery. Information

Substance Name: Mercury

Registry Number: 7439-97-6

Grant and Affiliation Information for Maternal fish consumption, mercury levels, and risk of preterm delivery.

AFFILIATION: Harvard School of Public Health, Harvard University, Boston, Massachusetts, USA.

Country: United States

AGENCY: United States NICHD

GRANT: R01 HD034543-07

ACRONYM: HD

MEDLINETA: Environ Health Perspect

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