Mapping of the mouse macrophage inflammatory protein-1 alpha receptor gene Scya3r and two related mouse beta chemokine receptor-like genes to chromosome 9.

Mapping of the mouse macrophage inflammatory protein-1 alpha receptor gene Scya3r and two related mouse beta chemokine receptor-like genes to chromosome 9. Research Abstract Details 

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Mapping of the mouse macrophage inflammatory protein-1 alpha receptor gene Scya3r and two related mouse beta chemokine receptor-like genes to chromosome 9. Abstract Text:

C A Kozak,J L Gao,P M Murphy,

Macrophage inflammatory protein-1 alpha (MIP-1 alpha) and RANTES are members of the beta chemokine family of leukocyte chemoattractants. We have previously cloned three mouse genes by cross-hybridization with the human MIP-1 alpha/RANTES receptor gene CMKBR1. One of the mouse genes, Scya3r, encodes a functional MIP-1 alpha receptor. The functions of the other two, Scya3r-rs1 and Scya3r-rs2, are not known. We have now mapped Scya3r, Scya3r-rs1, and Scya3r-rs2 to chromosome 9, in a region of conserved synteny with the location of CMKBR1. Thus, like chemokine genes and alpha chemokine receptor genes, this group of beta chemokine receptor genes arose by tandem duplication.

Mapping of the mouse macrophage inflammatory protein-1 alpha receptor gene Scya3r and two related mouse beta chemokine receptor-like genes to chromosome 9. Publishing Authors By Initials

CA Kozak,JL Gao,PM Murphy,

For similar investigative techniques: genetic techniques: chromosome mapping: physical chromosome mapping: restriction mapping research abstracts see: investigative techniques: genetic techniques: chromosome mapping: physical chromosome mapping: restriction mapping research

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Mapping of the mouse macrophage inflammatory protein-1 alpha receptor gene Scya3r and two related mouse beta chemokine receptor-like genes to chromosome 9. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Genomics

VOLUME: 29

Page Numbers: 294-6

Journal Abbreviation: Genomics

ISSN: 0888-7543

DAY: 1

MONTH: Sep

YEAR: 1995

Mapping of the mouse macrophage inflammatory protein-1 alpha receptor gene Scya3r and two related mouse beta chemokine receptor-like genes to chromosome 9. Information

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LANGUAGE: eng

NlmUniqueID: 8800135

Mapping of the mouse macrophage inflammatory protein-1 alpha receptor gene Scya3r and two related mouse beta chemokine receptor-like genes to chromosome 9. Keywords Mesh Terms:

KEYWORDS: Restriction Mapping

MESH TERMS: genetics

Chemical & Substance for Abstract: Mapping of the mouse macrophage inflammatory protein-1 alpha receptor gene Scya3r and two related mouse beta chemokine receptor-like genes to chromosome 9. Information

Substance Name: macrophage inflammatory protein 1alpha r

Registry Number: 0

Grant and Affiliation Information for Mapping of the mouse macrophage inflammatory protein-1 alpha receptor gene Scya3r and two related mouse beta chemokine receptor-like genes to chromosome 9.

AFFILIATION: Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

Country: UNITED STATES

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MEDLINETA: Genomics

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