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Manipulation of phosphene thresholds by transcranial direct current stimulation in man.

Manipulation of phosphene thresholds by transcranial direct current stimulation in man. Research Abstract Details 

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  • Manipulation of phosphene thresholds by transcranial direct current stimulation in man. Abstract Text:

    andrea antalAndrea Antal,tamás z kincsesTamás Z Kincses,michael a nitscheMichael A Nitsche,walter paulusWalter Paulus,

    Transcranial direct current stimulation (tDCS) can modulate the excitability of the human motor cortex, as revealed by the amplitude of the motor-evoked potentials (MEP). The aim of our study has been to produce localized changes of cerebral excitability of the visual cortex in the intact human by weak anodal and cathodal stimulation. For quantification of current-induced excitability changes, we measured phosphene threshold (PT) using short trains of 5-Hz transcranial magnetic stimulation (TMS) pulses in nine healthy subjects before, immediately after, 10 min, and 20 min after the end of tDCS. PTs are suggested as representative values of visual cortex excitability changes. Reduced PT was detected immediately and 10 min after the end of anodal stimulation, while cathodal stimulation resulted in an opposite effect. Our results show that tDCS elicits a transient, reversible excitability alteration of the visual cortex, thus representing a promising tool for neuroplasticity research.

    Manipulation of phosphene thresholds by transcranial direct current stimulation in man. Publishing Authors By Initials

    a antalA Antal,tz kincsesTZ Kincses,ma nitscheMA Nitsche,w paulusW Paulus,

    For similar nervous system: central nervous system: brain: prosencephalon: telencephalon: cerebrum: cerebral cortex: occipital lobe: visual cortex research abstracts see: nervous system: central nervous system: brain: prosencephalon: telencephalon: cerebrum: cerebral cortex: occipital lobe: visual cortex research

    PUBMED ID PMID:

    MEDLINE DATE:

    Manipulation of phosphene thresholds by transcranial direct current stimulation in man. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Experimental brain research. Experimentelle Hirnfo

    VOLUME: 150

    Page Numbers: 375-8

    Journal Abbreviation:

    ISSN: 0014-4819

    DAY: 16

    MONTH: 04

    YEAR: 2003

    Manipulation of phosphene thresholds by transcranial direct current stimulation in man. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 43312

    Manipulation of phosphene thresholds by transcranial direct current stimulation in man. Keywords Mesh Terms:

    KEYWORDS: Visual Cortex

    MESH TERMS: physiology

    Chemical & Substance for Abstract: Manipulation of phosphene thresholds by transcranial direct current stimulation in man. Information

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    Grant and Affiliation Information for Manipulation of phosphene thresholds by transcranial direct current stimulation in man.

    AFFILIATION: Department of Clinical Neurophysiology, Georg-August University of Göttingen, Robert Koch Strasse 40, 37070 Göttingen, Germany. Aantal@gwdg.de

    Country: Germany

    Germany Research PublicationGermany Research Publication

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    MEDLINETA: Exp Brain Res

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