[Management of adverse drug effects]

[Management of adverse drug effects] Research Abstract Details 

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[Management of adverse drug effects] Abstract Text:

R G Schlienger,

Adverse drug reactions (ADRs) are still considered one of the main problems of drug therapy. ADRs are associated with considerable morbidity, mortality, decreased compliance and therapeutic success as well as high direct and indirect medical costs. Several considerations have to come into play when managing a potential ADR. It is critical to establish an accurate clinical diagnosis of the adverse event. Combining information about drug exposure together with considering other possible causes of the reaction is crucial to establish a causal relationship between the reaction and the suspected drug. Identification of the underlying pathogenesis of an ADR together with the severity of the reaction will have profound implications on continuation of drug therapy after an ADR. Since spontaneous reports about ADRs are a key stone of a functioning post-marketing surveillance system and therefore play a key role in improving drug safety, health care professionals are highly encouraged to report ADRs to a local or national organization. However, because the majority of ADRs is dose-dependent and therefore preventable, individualization of pharmacotherapy may have a major impact on reducing such events.

[Management of adverse drug effects] Publishing Authors By Initials

RG Schlienger,

For similar pharmaceutical preparations research abstracts see: pharmaceutical preparations research

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[Management of adverse drug effects] Journal Published:

PUBLICATION TYPE: Review

Journal: Therapeutische Umschau. Revue thérapeutique

VOLUME: 57

Page Numbers: 584-90

Journal Abbreviation:

ISSN: 0040-5930

DAY: 12

MONTH: Sep

YEAR: 2000

[Management of adverse drug effects] Information

Number of References: 31

LANGUAGE: ger

NlmUniqueID: 407224

[Management of adverse drug effects] Keywords Mesh Terms:

KEYWORDS: Pharmaceutical Preparations

MESH TERMS: adverse effects

Chemical & Substance for Abstract: [Management of adverse drug effects] Information

Substance Name: Pharmaceutical Preparations

Registry Number: 0

Grant and Affiliation Information for [Management of adverse drug effects]

AFFILIATION: Abteilung Klinische Pharmakologie, Kantonsspital Basel. schliengerr@uhbs.ch

Country: SWITZERLAND

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MEDLINETA: Ther Umsch

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