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Mammography-guided stereotactic fine-needle aspiration cytology of nonpalpable breast lesions: prospective comparison with surgical biopsy results.

Mammography-guided stereotactic fine-needle aspiration cytology of nonpalpable breast lesions: prospective comparison with surgical biopsy results. Research Abstract Details 

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  • Mammography-guided stereotactic fine-needle aspiration cytology of nonpalpable breast lesions: prospective comparison with surgical biopsy results. Abstract Text:

    l l fajardoL L Fajardo,j r davisJ R Davis,j l wiensJ L Wiens,d c tregoD C Trego,

    We assessed the usefulness of fine-needle aspiration cytology (FNAC) in evaluating nonpalpable breast abnormalities by prospectively performing stereotactic mammography-guided FNAC on 100 women undergoing surgical excisional biopsy. Mammographic and cytologic diagnoses, on a scale of 1 (benign) to 4 (malignant), were assigned for each case and compared with the surgical pathologic diagnosis. Sensitivity and specificity were examined at different diagnostic cutoff points for regarding a mammographic or cytologic diagnosis as positive or negative. Of the 100 breast biopsy specimens, 70 were benign and 30 were malignant. For both mammography and FNAC, the optimal diagnostic cutoff point was between diagnosis 2 (mammography, probably benign; cytology, atypical) and 3 (mammography and cytology both suspicious for malignancy). At this cutoff point, FNAC had a sensitivity of 0.77 and specificity of 1.00, vs 0.73 sensitivity and 0.79 specificity for mammography. Pearson coefficient analysis revealed significant correlations between both mammographic and FNAC diagnoses and surgical pathology (p less than .001 for both). Our results suggest that use of mammography-guided FNAC may reduce the number of breast biopsies performed for benign lesions.

    Mammography-guided stereotactic fine-needle aspiration cytology of nonpalpable breast lesions: prospective comparison with surgical biopsy results. Publishing Authors By Initials

    ll fajardoLL Fajardo,jr davisJR Davis,jl wiensJL Wiens,dc tregoDC Trego,

    For similar surgical procedures, operative: neurosurgical procedures: stereotaxic techniques research abstracts see: surgical procedures, operative: neurosurgical procedures: stereotaxic techniques research

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    Mammography-guided stereotactic fine-needle aspiration cytology of nonpalpable breast lesions: prospective comparison with surgical biopsy results. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: AJR. American journal of roentgenology

    VOLUME: 155

    Page Numbers: 977-81

    Journal Abbreviation:

    ISSN: 0361-803X

    DAY: 15

    MONTH: Nov

    YEAR: 1990

    Mammography-guided stereotactic fine-needle aspiration cytology of nonpalpable breast lesions: prospective comparison with surgical biopsy results. Information

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    LANGUAGE: eng

    NlmUniqueID: 7708173

    Mammography-guided stereotactic fine-needle aspiration cytology of nonpalpable breast lesions: prospective comparison with surgical biopsy results. Keywords Mesh Terms:

    KEYWORDS: Stereotaxic Techniques

    MESH TERMS: methods

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    Grant and Affiliation Information for Mammography-guided stereotactic fine-needle aspiration cytology of nonpalpable breast lesions: prospective comparison with surgical biopsy results.

    AFFILIATION: Department of Radiology, University of Arizona University Medical Center, Tucson 85724.

    Country: UNITED STATES

    UNITED STATES Research PublicationUNITED STATES Research Publication

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    MEDLINETA: AJR Am J Roentgenol

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