Mammary carcinoma: comparison of DNA-content in the primary tumor and the corresponding axillary lymphnode metastases.

Mammary carcinoma: comparison of DNA-content in the primary tumor and the corresponding axillary lymphnode metastases. Research Abstract Details 

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Mammary carcinoma: comparison of DNA-content in the primary tumor and the corresponding axillary lymphnode metastases. Abstract Text:

Twenty primary mammary carcinomas and their corresponding axillary lymphnode metastases were studied. The DNA-content of individual tumor cells was measured in sections from the original paraffin embedded specimens. Comparison between the DNA-patterns obtained from the primary tumor and the corresponding metastases showed very close agreement in all but one case. Both euploid and aneuploid tumors were represented. In spite of having lymphnode metastases at operation, 8 patients survived more than 10 years after operation. All of these patients had euploid tumors, in contrast to 11 patients who died within 2 years, in whom all but one of the tumors showed aneuploid DNA-patterns. The results suggest that tumor progression in terms of lymphnode metastases is usually not associated with major changes in tumor nuclear DNA-content.

Mammary carcinoma: comparison of DNA-content in the primary tumor and the corresponding axillary lymphnode metastases. Publishing Authors By Initials

For similar diagnosis: prognosis research abstracts see: diagnosis: prognosis research

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Mammary carcinoma: comparison of DNA-content in the primary tumor and the corresponding axillary lymphnode metastases. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Acta pathologica, microbiologica, et immunologica

VOLUME: 94

Page Numbers: 29-34

Journal Abbreviation:

ISSN: 0108-0164

DAY: 26

MONTH: Jan

YEAR: 1986

Mammary carcinoma: comparison of DNA-content in the primary tumor and the corresponding axillary lymphnode metastases. Information

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LANGUAGE: eng

NlmUniqueID: 8206622

Mammary carcinoma: comparison of DNA-content in the primary tumor and the corresponding axillary lymphnode metastases. Keywords Mesh Terms:

KEYWORDS: Prognosis

MESH TERMS: pathology

Chemical & Substance for Abstract: Mammary carcinoma: comparison of DNA-content in the primary tumor and the corresponding axillary lymphnode metastases. Information

Substance Name: DNA, Neoplasm

Registry Number: 0

Grant and Affiliation Information for Mammary carcinoma: comparison of DNA-content in the primary tumor and the corresponding axillary lymphnode metastases.

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Country: DENMARK

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MEDLINETA: Acta Pathol Microbiol Immunol

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