Male germline stem cells: from mice to men.

Male germline stem cells: from mice to men. Research Abstract Details 

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Male germline stem cells: from mice to men. Abstract Text:

Ralph L Brinster,

The production of functional male gametes is dependent on the continuous activity of germline stem cells. The availability of a transplantation assay system to unequivocally identify male germline stem cells has allowed their in vitro culture, cryopreservation, and genetic modification. Moreover, the system has enabled the identification of conditions and factors involved in stem cell self-renewal, the foundation of spermatogenesis, and the production of spermatozoa. The increased knowledge about these cells is also of great potential practical value, for example, for the possible cryopreservation of stem cells from boys undergoing treatment for cancer to safeguard their germ line.

Male germline stem cells: from mice to men. Publishing Authors By Initials

RL Brinster,

For similar cells: stem cells research abstracts see: cells: stem cells research

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Male germline stem cells: from mice to men. Journal Published:

PUBLICATION TYPE: Review

Journal: Science (New York, N.Y.)

VOLUME: 316

Page Numbers: 404-5

Journal Abbreviation:

ISSN: 1095-9203

DAY: 20

MONTH: Apr

YEAR: 2007

Male germline stem cells: from mice to men. Information

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LANGUAGE: eng

NlmUniqueID: 404511

Male germline stem cells: from mice to men. Keywords Mesh Terms:

KEYWORDS: Stem Cells

MESH TERMS: physiology

Chemical & Substance for Abstract: Male germline stem cells: from mice to men. Information

Substance Name: Glial Cell Line-Derived Neurotrophic Fac

Registry Number: 0

Grant and Affiliation Information for Male germline stem cells: from mice to men.

AFFILIATION: Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Country: United States

AGENCY: United States PHS

GRANT: HDO44445

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MEDLINETA: Science

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